Results 181 to 190 of about 17,147,624 (345)

The green value chain model of mining company based on zero carbon emissions. [PDF]

Sci Rep
Fan C, Li G, Chen M, Hou J, Wei Q, Wang P, Guo G.   +6 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Hygiene knowledge and practices in the Lagos wild meat value chain: Cultural influences, regulatory gaps, and infrastructure needs. [PDF]

PLOS Glob Public Health
Akpan SN, Cook EAJ, van Langevelde F, van Hooft P, Zimmerman DM, Buij R, Hassell JM, Masudi SP, Happi CT, Happi AN, Thomas LF.   +10 more
europepmc   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Risk factor analysis of Campylobacter spp., Listeria monocytogenes and Salmonella spp. in the chicken meat value chain. [PDF]

Front Microbiol
Sneha ENP, Sanjumon ES, Nguyen-Viet H, Dubal ZB, Bhilegaonkar KN, Ayoub H, Grace Randolph D, Akash B, Gangwar A, Manoj S, Premkumar D, Dhanze H, Kumar B, Vinodh Kumar OR, Suman Kumar M, Deka RP.   +15 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Digital economy development and global value chain network centralization. [PDF]

PLoS One
Yuan H, Yue M, Wang R, Ren B, Li X.
europepmc   +1 more source

The global value chain and internalization theory

Journal of International Business Studies, 2019
Gabriel R. G. Benito, Bent Petersen, L. Welch   +2 more
semanticscholar   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

Bacteriological Quality of Raw Beef Products and Contact Surfaces in the Meat Value Chain, Eastern Ethiopia. [PDF]

Environ Health Insights
Kemal J, Tabit FT.
europepmc   +1 more source