Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley +1 more source
The Hawthorn (<i>Crataegus</i> spp.) Value Chain: An Integrated Analysis of Resource Availability, Phytochemical Characterization, and Therapeutic Applications. [PDF]
Zheng F +7 more
europepmc +1 more source
China's emerging role in the global semiconductor value chain
Seamus Grimes, Debin Du
semanticscholar +1 more source
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Value chain optimization in large scale gas network considering elevation and transmission direction. [PDF]
Ning X, Qiu J, Yu D.
europepmc +1 more source
Este artigo apresenta uma matriz de fatores a levar em conta para priorizar as cadeias de valor agrícolas selecionadas como foco das iniciativas público-privadas para impulsionar o seu desenvolvimento. Tais fatores conferem especial importância a temas de responsabilidade social empresarial.
openaire +1 more source
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli +9 more
wiley +1 more source
Examining Ethiopia's live animal and meat value chain. [PDF]
Wakaso AA, Mummed YY, Yesuf YK.
europepmc +1 more source
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
The unsung women of citriculture: bridging science and society through macro and micro analysis for improved technology adoption in citrus value chain. [PDF]
Bhattacharyya S +7 more
europepmc +1 more source

