Results 101 to 110 of about 6,506,591 (256)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Multidimensional Energy Poverty, Food Expenditure, and Dietary Diversity Among Rural Households

Food and Energy Security
This study examines the effects of multidimensional energy poverty on food expenditure, dietary diversity, and the consumption of key food groups among rural households in China.
Junpeng Li, Wanglin Ma
doaj   +1 more source

Endophytic Entomopathogenic Fungi: Their Role in Enhancing Plant Resistance, Managing Insect Pests, and Synergy with Management Routines

Journal of Fungi
The interaction between plants and microorganisms plays a major role in plant growth promotion and disease management. While most microorganisms directly influence plant health, some indirectly support growth through pest and disease suppression ...
Krishnamoorthy Aravinthraju, Mookiah Shanthi, Marimuthu Murugan, Ramasamy Srinivasan, Lourena Arone Maxwell, Narayanan Manikanda Boopathi, Rangasamy Anandham   +6 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Globalization, Privatization, and Vertical Coordination in Food Value Chains in Developing and Transition Countries [PDF]

Food and agricultural commodity value chains in developing and transition countries have undergone tremendous changes in the past decades. Companies and property rights have been privatized, markets liberalized, and economies integrated into global food ...
Swinnen, Johan F.M., Maertens, Miet
core  

Value Added Trade Restrictiveness Indexes. Measuring Protection within Global Value Chains [PDF]

, 2018
Production and trade are increasingly organized within Global Value Chains (GVCs) and therefore assessing who effectively pays the cost of protection is not straightforward.
Luca Salvatici, Alessandro Antimiani, Ilaria Fusacchia   +2 more
core  

Digital Attention as a Market Salience Indicator: Predicting Fintech Market Performance with Computational Models

Computation
This study examines whether digital attention can serve as an engagement-based digital attention signal for fintech market performance. Using a revised panel of 70 firm-year observations from seven publicly verifiable fintech and payments firms over 2016–
Vasilina K. Tsimpouka, Nikolaos T. Giannakopoulos, Damianos P. Sakas   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Impact of Influencer Marketing on Consumer Behavior and Online Shopping Preferences

Journal of Theoretical and Applied Electronic Commerce Research
Influencer marketing has emerged as a crucial element in digital marketing, significantly shaping consumer behavior and online shopping preferences. This study examined the multidimensional impact of influencer marketing by analyzing engagement metrics ...
Stavros P. Migkos, Nikolaos T. Giannakopoulos, Damianos P. Sakas   +2 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source