Results 161 to 170 of about 583,925 (313)

What's in it for me? A mixed-methods study on teachers' value creation in an inter-institutional community on open educational resources in higher education. [PDF]

open access: yesEduc Inf Technol (Dordr), 2023
Baas M   +6 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Shareholders and stakeholders value creation: an analytic foundation for value creation indicators

open access: yesPSL Quarterly Review, 2007
Article originally published in the volume 60 issue 240 of Banca Nazionale del Lavoro Quarterly Review (also known as BNL Quarterly Review).
Giancarlo Mazzoni, Rainer S. Masera
doaj  

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

An integrative framework of value [PDF]

open access: yes
The concept of value has been discussed for over 2000 years with various nuanced meanings. It was a focus of concern for Plato and Aristotle, and Adam Smith (1776) dealt extensively with value in The Wealth of Nations.
Smith, Laura A., Ng, Irene C. L.
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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