Results 191 to 200 of about 583,925 (313)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Identifying a Terminal Nickel–Oxygen Complex Bearing an Unsymmetrical β‑Diketiminate Ligand

JACS Au
Si-Hong Chen, Tzu-Hsien Yang, Yu-Lun Chang, Wei-Syuan Lin, Chuan-Hung Chuang, Cheng-Han Yang, Hsing-Yin Chen, Ming-Li Tsai, Sodio C. N. Hsu   +8 more
doaj   +1 more source

Enzyme Catalysis for Sustainable Value Creation Using Renewable Biobased Resources. [PDF]

Molecules
Wohlgemuth R.
europepmc   +1 more source

An apple a day - how the platform economy impacts value creation in the healthcare market. [PDF]

Electron Mark, 2021
Gleiss A, Kohlhagen M, Pousttchi K.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Empirical Study on Hospitalist System: A Value Creation Perspective. [PDF]

Healthcare (Basel)
Kung LH, Yan YH.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Understanding the knowledge structure and the value creation process of the metaverse. [PDF]

Heliyon
Ramírez-Herrero V, Ortiz-de-Urbina-Criado M, Medina-Merodio JA.   +2 more
europepmc   +1 more source

Correction: Value in psoriasis (IRIS) trial: implementing value-based healthcare in psoriasis management - a 1-year prospective clinical study to evaluate feasibility and value creation. [PDF]

BMJ Open, 2023
europepmc   +1 more source

Value Creation Strategy (Collective Value Creation Strategies

A consolidated report on the expected value and cost - competitive profile (VCS) for the different propulsion systems, including the relative base line system(s) for comparison.
openaire   +1 more source