Results 101 to 110 of about 6,364,896 (296)
Sustainable Shareholder Value: Analysis of Value Drivers
Purpose. The main objective of the paper is to determine the critical factors, which have an impact on the long-term value maximization for company’s shareholders. Methodology.
Titko, Jeļena +2 more
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Does a video speed task predict risky speeding behaviour in young and inexperienced drivers? [PDF]
, 2010 Vehicle crashes account for the highest number of fatalities for persons aged between 17 and 25 years of age in New Zealand. Despite a myriad of factors precipitating vehicle crashes, excess or inappropriate vehicle speed has been identified as the ...
Cantwell, Stephen James
core
Distraction and related risk factors among professional and non-professional drivers
HeliyonBackground: Distraction is one of the main driver's behavioral factors that reduces the performance of the drivers and might increase the accident risk.
Alireza Razzaghi +4 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
The effect of age and experience on hazard perception and speed choice in male drivers [PDF]
, 2012 There are many deaths on New Zealand roads each year, due to speeding related incidents. Teenage drivers (aged 15 to 24 years) are excessively represented in crash statistics.
Crosswell, Rebekah Jane
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A Computer-Based Interactive Multimedia Training CD-ROM for Novice Drivers in New Zealand [PDF]
, 2003 This paper will describe the psychological and educational rationales behind the development of a computer-based interactive multimedia training CD-ROM (‘CD-DRIVES’) that will be made available to all novice drivers in New Zealand at no cost to the ...
Cockerton, Craig, Isler, Robert B.
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source