Results 71 to 80 of about 6,652,575 (258)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Cruising for parking: New empirical evidence and influential factors on cruising time

open access: yesJournal of Transport and Land Use, 2017
The goal of this study is to explore the perceptions and behaviors of drivers who cruise for parking. We conducted surveys with drivers in Brisbane, Australia, to understand potential factors that influence drivers’ cruising behavior.
Jinwoo (Brian) Lee   +2 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Estimation of Tactile Discriminatory Fitness in Hands of Public Transport Drivers

open access: yesJournal of College of Medical Sciences-Nepal, 2020
Background: Public transport drivers are constantly being exposed to stimuli and are at risk of disorder of peripheral nervous system which can be further complicated by comorbidities.
Ojashwi Nepal   +4 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Illusion of Motion: Variation of Subjective Value of Travel Time on Freeways and Ramp Meters [PDF]

open access: yes
This paper explores drivers' subjective value of time under moving and stopped freeway travel conditions using a stated preference survey. Unlike previous studies that assume a constant value of time, this research relates perceived satisfaction of a ...
Feng xie, Lei Zhang, David Levinson
core  

Managing Value Creation Paradoxes in Social Business: The Role of the Digital Platform Business Model

open access: yesBAR: Brazilian Administration Review
Objective: this paper examines how business model design influences value creation paradoxes in social businesses, with a focus on DPBMs (digital platform-based models).
Valéria Feitosa de Moura   +2 more
doaj   +1 more source

Value Drivers in Business Course Design: A Student Stakeholder Perspective

open access: yesInternational Journal for the Scholarship of Teaching and Learning, 2007
As one of the important stakeholders in the academic process, students and their preferences should be considered when the instructor selects the various course design features.
John Knight, Daniel Tracy
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

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