Results 101 to 110 of about 4,889,999 (350)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

The Effectiveness Of Using Column Formwork In A Multi-Story Building Construction Project

open access: yesRekayasa Sipil
Building the structural components is crucial for constructing a multi-story building. In the process of creating these components, which is commonly done through casting, a tool called formwork is required.
Muhammad Lawdy Dhiyaa Vansya   +2 more
doaj   +1 more source

The values of engineers and managing engineers

open access: yesIEEE Transactions on Engineering Management, 1979
Personal value orientations of engineers employed in high technology industries are investigated. The importance placed on specific values by engineers and managing engineers are compared using the Rokeach Value Survey. Although there were significant differences between these two groups on both values involving desirable end states of existence ...
Munson, J. Michael, Posner, Barry Z.
openaire   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Identification and Ranking of Value Engineering indicators in the projects of the worn-out urban fabric of the North East Investment Company using the Fuzzy Delphi Method [PDF]

open access: yesمهندسی و مدیریت ساخت
The purpose of this research was to identify the effective indicators in conducting "value engineering" studies in the projects of the worn-out urban fabric of North East Investment Company. For this purpose, previous studies used to identify indicators.
Sayed Amir Reza Madarshahian   +1 more
doaj  

Home - About - Disclaimer - Privacy