Results 111 to 120 of about 34,082,428 (320)
CeROArt : Conservation, Exposition, Restauration d'Objets d'Art, 2013 Built in the fourteenth century, remodelled several times, restored by Viollet-le-Duc in the nineteenth century: do the ramparts of Avignon have any claim to authenticity? It is tempting to say “absolutely not”. But this would mean ignoring the fact that
Georges Brunel
doaj +1 more source
Hierarchical Reinforcement Learning with the MAXQ Value Function Decomposition
, 1998 This paper presents the MAXQ approach to hierarchical reinforcement learning based on decomposing the target Markov decision process (MDP) into a hierarchy of smaller MDPs and decomposing the value function of the target MDP into an additive combination ...
Dietterich, Thomas G.
core +6 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
On some mean value results for the zeta-function in short intervals [PDF]
, 2013 Let $\Delta(x)$ denote the error term in the Dirichlet divisor problem, and let $E(T)$ denote the error term in the asymptotic formula for the mean square of $|\zeta(1/2+it)|$. If $E^*(t) := E(t) - 2\pi\Delta^*(t/(2\pi))$ with $\Delta^*(x) := -\Delta(x)
Ivić, Aleksandar
core
Vector-valued functions as families of scalar-valued functions [PDF]
Pacific Journal of Mathematics, 1981 Geitz, Robert F., Uhl, J. J.
openaire +3 more sources
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Continuous Differentiability of the Value Function of Semilinear Parabolic Infinite Time Horizon Optimal Control Problems on L 2 ( Ω ) Under Control Constraints. [PDF]
Appl Math Optim, 2022 Kunisch K, Priyasad B.
europepmc +1 more source
Algebraic values of G-functions.
Journal für die reine und angewandte Mathematik (Crelles Journal), 1993 It is a well-known fact that functions like \(\log z\) and \(\exp z\) assume transcendental values at non-zero algebraic points. This has been proved for a large class of functions satisfying linear differential equations with polynomial coefficients. Surprisingly, J.
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Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source