Results 51 to 60 of about 2,460,801 (256)
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Measuring the processes and outcomes of value management studies in construction
, 2005 7th International Value Conference 2005: Why Re-Invent the Wheel?, Hong Kong, 2-3 June 2005Value management (VM) is a useful tool in coping with many challenges faced by the construction industry today.
Shen, Q +7 more
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Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Including value orientations in choice models to estimate benefits of wildlife management policies (Forthcoming) [PDF]
, 2018 Value orientations towards wildlife affect the way people perceive nature and their connection with animals. In particular, the social psychological literature within the environmental field suggests that there are two main orientations of people towards
Notaro, Sandra +2 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
The Value Relevance of Forced Top Management Departures [PDF]
This paper studies the value relevance of management turnover based on a sample of Dutch events. Consistent with previous studies we find weak or insignificant aggregate announcement effects on stock prices.
C. Mirjam van Praag, Kees Cools
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Corporate Risk Management as a Lever for Shareholder Value Creation [PDF]
Firm value is influenced in many direct and indirect ways by financial risks, which consist of unexpected changes of foreign exchange rates, interest rates and commodity prices.
Sohnke M. Bartram
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Common Value Management. 1st International Workshop Common Value Management, CVM 2012
, 2022 The 1st International Workshop on Common Value Management (CVM2012) focuses on one of today's major trends, not only in relation to semantic technology research, but also in relation to the industries' huge demand for tools and consulting in the domain ...
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source