Results 101 to 110 of about 8,748,539 (298)

The Discount Rate and the Value of Remaining Years of Life [PDF]

open access: yes
We back out an estimate of a personal discount rate of between 3 and 4 percent for a person with a life expectancy of 74 years who dies at age 30 (or 40) and has a value of statistical life of $6.3 million.
John Hartwick
core  

The Contested Value of Life

open access: yesCambridge Quarterly of Healthcare Ethics
AbstractPutting a specific value on human life is important in many contexts and forms part of the basis for many political, administrative, commercial, and personal decisions. Sometimes, the value is set explicitly, sometimes even in monetary terms, but much more often, it is set implicitly through a decision that allows us to calculate the valuation ...
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Application of discrete choice experiments to estimate value of life: a national study protocol in Iran. [PDF]

open access: yesCost Eff Resour Alloc, 2021
Mirzaee N   +5 more
europepmc   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

El milagro de seguir siendo

open access: yesMedUNAB
Quizás la pregunta más antigua que el ser humano se ha formulado no es ¿de dónde venimos? ni ¿hacia dónde vamos?, sino una más íntima y más urgente, ¿Por qué permanezco?.
Stifer Yajaira Orduz-Soto
doaj   +1 more source

Index for asset value measure obtained from condition monitoring digitalized data interpretation. A railway asset management application [PDF]

open access: yes, 2019
Hosted by the Johannes Kepler University, Linz, Austria. May 23-24, 2019The objective of any asset is to provide value to the organization, being the corner stone to get a highest possible economic benefit in a sustainable way. An effective asset value
Candón, Eduardo   +5 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Anti-Melanogenic Activities of Sargassum fusiforme Polyphenol-Rich Extract on α-MSH-Stimulated B16F10 Cells via PI3K/Akt and MAPK/ERK Pathways

open access: yesFoods
Background: Melanin overproduction leads to pigmented skin diseases. Brown algae polyphenols, non-toxic secondary metabolites, exhibit potential bioactivities.
Bei Chen   +9 more
doaj   +1 more source

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