Results 41 to 50 of about 548,808 (266)
Creative leadership of Manager as managerial competence: value-oriented approach. Part I [PDF]
Омский научный вестник: Серия "Общество. История. Современность", 2019 The two parts present the results of the study of the formation and development of creative leadership of the Manager as a managerial competence, which are relevant in modern conditions of active innovative transformations that increase the «demand ...
V. N. Ivanov, E. V. Yakovleva
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
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Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
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Value Orientations: Australian Studies
The Australian Journal of Indigenous Education, 1978 As early as 1938 Elkin, discussing traditional Aboriginal society, maintained that Aborigines are orientated collectively, or place high value on the extended kin group (Barwick, 1964; Becket, 1964; Fink, 1964), see themselves as existing in harmony with nature and have no conception of time in the European sense, but live only for the present and ...
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
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FAMILY VALUES IN FUTURE SOCIAL WORKERS
Вестник Северо-Кавказского федерального университета, 2022 This article from a scientific point of view, consider the category of «value», given the traditional values ofEuropean culture, it shows the importance of the family in the system of value orientations of the future social worker.
Elena Gorlova
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Sovremennye Issledovaniâ Socialʹnyh Problem, 2015 В данной статье рассматривается проблема гражданско-национальной идентичности современной молодёжи в условиях социокультурных трансформаций (на примере Республики Хакасия), даётся сравнение современных теоретических подходов к понятиям идентичность ...
Elena Aleksandrovna Kochina
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Yaroslavl Pedagogical Bulletin, 2020 The basic method is applied to the study of the typology of personal values. A basis is a complete, ordered, measurable set of elements. In our case, the elements are personality types. Completeness is determined by a factorial dichotomous typological set. Orderliness is determined by a single dichotomous multi-dimensional basic word structure of a set
Konstantin B. Malyshev +1 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
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Društvene i Humanističke Studije, 2020 The article “The values and value orientations” deals with the concepts of values, value orientations and value-systems. The work contains introduction, definition of values and value orientations, the theory of value and value-systems, historical development of value-systems, general review of previous research on values and value orientation, and ...
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