Results 41 to 50 of about 7,071,120 (250)

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Learning orientation and innovation performance: The mediating role of operations strategy and supply chain integration [PDF]

open access: yes, 2020
Purpose: The purpose of this study is to explore the effect of operations strategy (cost, quality, flexibility, and delivery) and supply chain integration on innovation performance under influence of learning orientation.
Jabarzadeh, Younis   +3 more
core   +1 more source

Social value orientation as a moral intuition: Decision-making in the dictator game [PDF]

open access: yes
We studied the decision making process in the Dictator Game and showed that decisions are the result of a two-step process. In a first step, decision makers generate an automatic, intuitive proposal.
Luk Warlop   +2 more
core   +2 more sources

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Creative leadership of Manager as managerial competence: value-oriented approach. Part I [PDF]

open access: yesОмский научный вестник: Серия "Общество. История. Современность", 2019
The two parts present the results of the study of the formation and development of creative leadership of the Manager as a managerial competence, which are relevant in modern conditions of active innovative transformations that increase the «demand ...
V. N. Ivanov, E. V. Yakovleva
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Market orientation of the Swedish pork sector [PDF]

open access: yes, 2011
In 2007, the largest slaughterhouse in Sweden, the farmer cooperative Swedish Meats, demutualized. That was the end of cooperative dominance in the Swedish meat industry. Paper VI claims that Swedish Meats demutualized because members no longer perceived
Lind, Lena Westerlund
core   +1 more source

Reverse-market orientation and corporate brand development [PDF]

open access: yes, 2008
In this paper we explore reverse-market orientation which we define as a market strategy that seeks more explicitly to align with customers to assist them in developing their optimum solution in a given marketplace.
Lawer, Christopher, Knox, Simon
core   +1 more source

FAMILY VALUES IN FUTURE SOCIAL WORKERS

open access: yesВестник Северо-Кавказского федерального университета, 2022
This article from a scientific point of view, consider the category of «value», given the traditional values ofEuropean culture, it shows the importance of the family in the system of value orientations of the future social worker.
Elena Gorlova
doaj  

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