Results 51 to 60 of about 1,488 (213)
Complex hydride anion substitution in argyrodite electrolytes has attracted attention for improving interfacial stability, yet the influence of these anions at Li metal interfaces remains unclear. This work shows that electrochemically formed BH4−‐derived interphases enable stable high‐current full‐cell cycling.
Sangho Lee +13 more
wiley +1 more source
Multi‐trait genome‐wide association mapping identifies a central hub regulator, COLD AND CATECHINS REGULATOR 1 (CCR1), and its excellent natural allele variation, coordinately enhancing cold tolerance and promoting catechins biosyntheis. CsCCR1 interacts with CsCBF1/3 and is transcriptionally activated by CsLUX and CsKUA1 to promote catechins ...
Yanli Wang +10 more
wiley +1 more source
This study examines about last survivor life insurance with return of premium for married couples with independent and dependent mortality model. By using Frank copula, Clayton copula, Gumbel copula and Indonesian Mortalita Table 2011, the impact of ...
I GEDE DICKY ARYA BRAMANTA +3 more
doaj +1 more source
Automation and Active Learning for the Multi‐Objective Optimization of Antibody Formulations
Successful antibody formulation necessitates balancing factors such as thermal stability, colloidal stability, and viscosity across a vast excipient design space. This work integrates robotic liquid handling, high‐throughput biophysical characterization, and multi‐objective Bayesian optimization in an iterative closed‐loop Design‐Build‐Test‐Learn cycle.
D. Christopher Radford +3 more
wiley +1 more source
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng +16 more
wiley +1 more source
A high‐power hybrid nanogenerator (HP‐HNG) with multi‐degree‐of‐freedom mechanical coupling is reported, integrating multi‐directional wave energy for output to achieve 1 + 1 > 2 energy harvesting. The HP‐HNG achieves a peak output power of 0.764 W, corresponding to a peak power density of 127.303 W m−3. At a wave frequency of 1 Hz, the HP‐HNG delivers
Shuai Ding +9 more
wiley +1 more source
A deep learning–driven pipeline mining 246 million protein sequences uncovers AhPETase, an evolutionarily distinct PET hydrolase. Engineered variant AhPETaseM1 degrades post‐consumer PET microplastics under physiological conditions and reverses microplasticinduced cytotoxicity in human lung and colon cells, establishing enzymatic microplastic ...
Yuxuan Wang +9 more
wiley +1 more source
A quantitative exposure‐heat treatment framework identifies a critical humidity threshold (15%RH) and heat treatment temperature (80°C) that governs the recoverability of air‐exposed Na3PS4, revealing the decoupled thermodynamic and kinetic contributions to its moisture stability.
Boling Liu +10 more
wiley +1 more source
How Video‐Based Information Affects Farmers' Willingness to Pay for Drone Services
ABSTRACT Professional service for digital technology like agricultural drones lowers transaction costs and scope thresholds for smallholders. Meanwhile, perceptual adoption barriers remain underexplored. We conduct a two‐stage choice experiment with a randomized video‐based information treatment among 384 Chinese crop farmers to measure its effect on ...
Hua Zhang +4 more
wiley +1 more source

