Results 91 to 100 of about 85,732 (247)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Value Proposition at NETFLIX [PDF]
, 2021 The thesis is a case study about Netflix and its position in the streaming industry. The goal is to introduce Netflix as a company and analyse whether Netflix could be considered as a forerunner on the global market.
Csalló, Rebeka
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Analytics-Based Customer Value Proposition Development in B2B Supply Chain [PDF]
, 2015 The customer value proposition is the heart of an organization. The internship provided an opportunity to examine this critical process at a wholesaler-distributor firm, in business-to-business supply chain. Distributors cannot expect a premium return on
Gunasekaran, Senthilmu
core
A Value Proposition Development Framework for Industrial Service [PDF]
, 2017 Value proposition is a key concept in the research on service and in the practice of service management. Value propositions are described as tools to communicate and motivate a joint value creation opportunity among involved organizations and ...
Risto Rajala +7 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The employee value proposition redefined
, 2005 Andrew N. Bell considers the role of company reputation in creating a convincing, credible and competitive employee value proposition.
Andrew N. Bell
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Creating Service Value Proposition for Company A [PDF]
, 2013 The aim of this thesis is to create a value proposition for Company A using the process and tools suitable in delivering its purpose. The study attempts to answer the research question, what is the service value proposition for Company A and its ...
Leal-Ruokonen, Juliet
core
EonThe ethical propositions of the form e = „The fact p is good” have not a determined truth value. Like any other proposition, the truth value of the proposition e is determined only relatively to a context, arriving to „The fact p is good relatively to ...
Ionel NARIȚA
doaj