Results 71 to 80 of about 3,104,463 (339)
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
The Value Relevance of Forced Top Management Departures [PDF]
This paper studies the value relevance of management turnover based on a sample of Dutch events. Consistent with previous studies we find weak or insignificant aggregate announcement effects on stock prices.
C. Mirjam van Praag, Kees Cools
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Evaluation in experimental research articles [PDF]
, 1989 This thesis examines evaluation in experimental research articles in terms of the meanings made and their contribution to the organisation of the articles.
Hunston 1953-, Susan
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Efficient AUC Optimization for Information Ranking Applications
, 2016 Adequate evaluation of an information retrieval system to estimate future performance is a crucial task. Area under the ROC curve (AUC) is widely used to evaluate the generalization of a retrieval system. However, the objective function optimized in many
C Cortes +6 more
core +1 more source
Quality of will and radical value reversals [PDF]
, 2020 Al Mele’s Manipulated Agents: A Window to Moral Responsibility (OUP 2019) is an extraordinarily careful and clear little book. A central recurring element is the use of examples of radical value reversals due to manipulation.
Björnsson, Gunnar
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Disclosure e materialidade do ativo intangível na value relevance do mercado acionário brasileiro
EnfoqueObjetivo: Investigar o nível de disclosure dos ativos intangíveis e a inferência junto à materialidade do ativo intangível na value relevance de sociedades de capital aberto brasileiras listadas no Índice Brasil Amplo (IBrA); Método: Utilizando uma ...
Anderson Rafael Costa Sousa +2 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Ownership Concentration, Firm Size and Information Value Relevance: Indonesian Evidence
Journal of Accounting and Investment, 2019 This paper describes empirical evidence investigated the effect of ownership concentration and firm’s size on the accounting information value relevance.
Krismiaji Krismiaji +2 more
doaj +1 more source