Results 191 to 200 of about 38,520,741 (357)

Values and ethics for implementation fidelity and integrity of public health policy in a multipolar world with conflicting value systems. [PDF]

J Public Health (Oxf)
Mfutso Bengo J, Mfutso Bengo E.
europepmc   +1 more source

Value-Aware Multiagent Systems

This paper introduces the concept of value awareness in AI, which goes beyond the traditional value-alignment problem. Our definition of value awareness presents us with a concise and simplified roadmap for engineering value-aware AI. The roadmap is structured around three core pillars: (1) learning and representing human values using formal semantics,
openaire   +2 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Value Co-creation and Co-destruction with Digital Actors : A Service-dominant Logic Perspective on Information Systems Use

The literature on information systems (IS) use has traditionally considered IS as tools and resources that support organizational and individual processes.
Lumivalo, Juuli, Elo, Jenny
core  

Critical value factors in business intelligence systems implementations

, 2017
Business Intelligence (BI) systems have been rated as a leading technology for the last several years. However, organizations have struggled to ensure that high quality information is provided to and from BI systems. This suggests that organizations have
Levy, Y, Hackney, RH, Dooley, P, Parrish, JR   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

MANURE VALUE, PRICING SYSTEMS, AND SWINE PRODUCTION DECISIONS

Based on a swine producer's profit maximization model in which manure value and packers' live market weight pricing systems are considered, the optimal farm inventory and optimal hog market weight are simultaneously solved for scenarios generated from ...
Miller, Gay Y., Huang, Haixiao
core   +1 more source

SOLUTIONS AND POLICIES FOR THE IMPLEMENTATION OF BUSINESS INFORMATION SYSTEMS [PDF]

The present paper is focused on the identification of the tendencies in introducing Information Technology and Communications in enterprises. It is investigated how the European Union policies sustain the adoption of the information systems by its ...
Liliana Mihaela MOGA
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Large-Value Payment System Design and Risk Management [PDF]

This article considers how wholesale (also often called large-value) payment systems can be organised, how they have evolved over recent decades and what are the forces currently at play in shaping settlement mechanisms.
Cronin, David
core