Results 161 to 170 of about 13,432,161 (307)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Extreme Value Theory for Hurwitz Complex Continued Fractions. [PDF]

Entropy (Basel), 2021
Kirsebom MS.
europepmc   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The path of promoting adolescents' physical exercise: Based on the control-value theory of achievement emotions. [PDF]

Br J Educ Psychol
Zhang T, Han H.
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Psychological flexibility and emotional trajectories during a semi-high-stakes mathematics exam: Integrating acceptance and commitment therapy with control-value theory. [PDF]

Br J Educ Psychol
Zarra-Nezhad M, Holopainen T, Räsänen P, Laakso MJ, Alanko K.   +4 more
europepmc   +1 more source

Joint Risk Analysis of Extreme Rainfall and High Tide Level Based on Extreme Value Theory in Coastal Area. [PDF]

Int J Environ Res Public Health, 2023
Chen H, Xu Z, Chen J, Liu Y, Li P.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Emotional engagement as a mediator in design thinking-based entrepreneurship education: a control-value theory perspective on innovation and interpersonal competency. [PDF]

Front Psychol
Ye Z, Wee EH, Wang J, Zhang G, Lin D.
europepmc   +1 more source

How to promote grass roots medical treatment under China's graded diagnosis and treatment policy? - From the perspective of customer value theory. [PDF]

Front Public Health, 2022
Tao W, Chen X, Gan S.
europepmc   +1 more source