Results 41 to 50 of about 11,480,086 (288)

Acute Neurological Events in Children With Hemoglobin SC Disease: A Multicenter Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neurological manifestations in children with hemoglobin SC (HbSC) disease remain insufficiently characterized, particularly regarding acute events. The aim of this study was to describe the spectrum and frequency of acute neurological events in a multicenter cohort of children with HbSC disease.
Célia Paulmin, Bérengère Koehl, Audrey Maudoux, Hanine Mansour, Marie‐Hélène Odievre, Nathalie Garrec, Emilie Georget, Cécile Arnaud, Slimane Allali, Lydia Doumdo, Marie Belloy, Corinne Guitton   +11 more
wiley   +1 more source

The patient reported intraocular lens questionnaire (PR-ILQ): content validity, psychometric performance, and use in a regulated clinical trial to evaluate safety and effectiveness outcomes

Journal of Patient-Reported Outcomes
Background Patient-reported outcomes (PROs) are underutilized in medical device evaluations, including in ophthalmology and intraocular lens (IOL) replacements.
Alan L. Shields, Nina Galipeau, Leighann Litcher-Kelly, Alejandro Moreno-Koehler, Jimmy Chacko   +4 more
doaj   +1 more source

Content validity of patient-reported outcomes for use in lower-risk myelodysplastic syndromes

Journal of Patient-Reported Outcomes, 2020
Background The lower-risk (low and intermediate-1 risk based on IPSS) myelodysplastic syndrome (MDS) has a negative impact on patients’ health-related quality of life (HRQoL).
Jeremiah J. Trudeau, Jianming He, Esther Rose, Charlotte Panter, Sharan Randhawa, Adam Gater   +5 more
doaj   +1 more source

Values in Psychotherapy

, 1996
There is a tension between those who hold that psychotherapy is a scientific discipline and therefore "value-free," and those who believe that values are inherent in the nature of psychotherapy.
Holmes, Jeremy
core   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Patient-centered outcomes for clinical trials in chronic rhinosinusitis with or without nasal polyps and allergic fungal rhinosinusitis

Journal of Patient-Reported Outcomes
Background Chronic rhinosinusitis (inclusive of subtypes with nasal polyps [CRSwNP], without nasal polyps [CRSsNP], and allergic fungal rhinosinusitis [AFRS]) causes inflammation of the nose mucosa and paranasal sinuses.
Brittany Klooster, Kaitlin Chatterton, Nazifa Ibrahim, Madison C. Bernstein, Alan L. Shields, Veleka Allen   +5 more
doaj   +1 more source

Assessing asthma symptoms in children: qualitative research supporting the development of the Pediatric Asthma Diary—Child (PAD-C) and Pediatric Asthma Diary—Observer (PAD-O)

Journal of Patient-Reported Outcomes, 2023
Background Pediatric asthma has been identified by regulators, clinicians, clinical trial sponsors, and caregivers as an area in need of novel fit-for-purpose clinical outcome assessments (COAs) developed in accordance with the U.S.
Helena Bradley, Claire Trennery, Amy M. Jones, Aoife Lydon, Frances White, Rebecca Williams-Hall, Rob Arbuckle, Erin Tomaszewski, Vivian H. Shih, John Haughney, Amanda Eisen, Tonya Winders, Stephen Joel Coons, Sonya Eremenco, the Patient-Reported Outcome Consortium’s Pediatric Asthma Working Group   +14 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier, Nathalie Cozic, Marie‐Dominique Tabone, Gaelle Pierron, Perrine Marec‐Berard, Sarah Winter, Gabriel Revon‐Rivière, Cyril Lervat, Dominique Plantaz, Marie‐Pierre Castex, Gregory Guimard, Estelle Thebaud, Stephanie Proust, Laure Saumet, Natacha Entz‐Werle, Sophie Taque, Cécile Vérité, Marta Jimenez, Nathalie Gaspar   +18 more
wiley   +1 more source

Psychometric evaluation of the HFDD, PROMIS SD SF 8b, and MENQOL questionnaire in women experiencing vasomotor symptoms associated with menopause

Journal of Patient-Reported Outcomes
Background Vasomotor symptoms (VMS; hot flashes) associated with menopause have significant impacts on health-related quality of life and are a leading cause for women seeking medical attention.
Andrew Trigg, Melissa Barclay, Sophie Whyman, Asha Lehane, Helena Bradley, Christoph Gerlinger, Christian Seitz, Adam Gater, Claudia Haberland   +8 more
doaj   +1 more source

Intentionality and Agency in Values Work Research

, 2022
This chapter addresses how intentionality and agency can be understood in relation to values and values work. How different degrees of intentionality relate to different dimensions of agency is something we need to understand empirically rather than as a
Andersson, Thomas,, Thomas Andersson, Andersson, Thomas   +2 more
core   +1 more source