Results 21 to 30 of about 4,986,038 (258)

Observing Huntington's disease: the European Huntington's Disease Network's REGISTRY. [PDF]

, 2010
The unparalleled collection of clinical data and biomaterials within the EHDN's REGISTRY can expedite the search for disease modifiers (genetic and environmental) of age at onset and disease progression that could be harnessed for the development of ...
Handley, Olivia J, Landwehrmeyer, G Bernhard, Aileen K Ho, Bisson, Jonathan Ian, Schwenke C, David Craufurd, Dunnett, Stephen B., Handley, Olivia, Investigators of the European Huntington's Disease Network, The, DI MARIA, EMILIO, Craufurd D, Dunnett, SB, Carsten Schwenke, the investigators of the European Huntington's Disease Network, Craufurd, David, Edward Wild, Landwehrmeyer, GB, Busse, Monica, Rosser, Anne Elizabeth, Olivia J Handley, Romano Silvia., Tabrizi SJ, Ho, Aileen K., Wild, E, Landwehrmeyer GB, Craufurd, D, Tabrizi, SJ, Tabrizi, Sarah J., Handley, OJ, Rickards, Hugh, Dunnett, Stephen, Ho, Aileen K, Orth, Michael, Ho, AK, Wild, Edward, Stephen B. Dunnett, Sarah J Tabrizi, Wild, EJ, Landwehrmeyer, G. Bernhard, Naji, Jenny, Landwehrmeyer, G. Bernhard, Wild E, Investigators of the European Huntington's Disease Network, Handley, Olivia J., Orth, M, Ellison-Rose, Lynda, Tabrizi, Sarah J, Price, Kathleen, Ho AK, ABBRUZZESE, GIOVANNI, Schwenke, C, Ho, A, Orth M, Handley OJ, Schwenke, Carsten, Dunnett SB, Dunnett, Stephen B, Michael Orth, G. Bernhard Landwehrmeyer   +59 more
core   +1 more source

Data on plasma tumour and metabolism related proteins’ potential in differentiation of HFpEF-PH from PAH and in prognosis of left heart failure patients with pulmonary hypertension

Data in Brief, 2022
The data in the current paper constitutes supplementary material to our article entitled “Plasma tumour and metabolism related biomarkers AMBP, LPL and Glyoxalase I differentiate heart failure with preserved ejection fraction with pulmonary hypertension ...
Salaheldin Ahmed, Abdulla Ahmed, Göran Rådegran   +2 more
doaj   +1 more source

A case control investigation of the relation between hyperlipidaemia and calcific aortic valve stenosis [PDF]

, 1997
Objective To investigate the relation of hyperlipidaemia to calcific aortic valve stenosis. Design A case-control study designed to detect a clinically relevant difference in the fasting plasma concentrations of total cholesterol between the groups at ...
Stevenson, R N, Lord, John R, Wilmshurst, P T, Griffiths, H   +3 more
core   +1 more source

Plasma VEGF-D and sFLT-1 are potential biomarkers of hemodynamics and congestion in heart failure and following heart transplantation

JHLT Open, 2023
Background: Inflammation and tyrosine-kinases are known mediators in the pathobiology of cardiovascular disease. Plasma biomarkers reflecting these systems may provide a noninvasive complement reflecting hemodynamics, aiding in clinical decision-making ...
Salaheldin Ahmed, MD, Jakob Lundgren, MD, PhD, Abdulla Ahmed, MD, Göran Rådegran, MD, DMSc, MSc Eng Phys   +3 more
doaj   +1 more source

LDL receptor-independent mechanisms of proprotein convertase subtilisin/kexin type 9 in cardiovascular pathophysiology

Frontiers in Cardiovascular Medicine
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a pivotal regulator of lipid metabolism and a validated therapeutic target in cardiovascular disease (CVD). While its canonical role in mediating low-density lipoprotein receptor (LDLR) degradation
Hang Su, Xunan Guo, Qiang Li, Xiaohang Yuan, Xiaolong Wu, Zihan Zhao, Yi Kan, Yifan Yang, Zhaolin Fu, Zhenrui Qi, Guangyuan Song   +10 more
doaj   +1 more source

Acute Decompensated Valvular Disease in the Intensive Care Unit. [PDF]

JACC Adv
Acute decompensated valvular disease encompasses a group of complex and challenging conditions, which are often the primary reason for admission to the cardiac intensive care unit and can also complicate the management of other primary cardiac disorders.
Miller PE, Senman BC, Gage A, Carnicelli AP, Jacobs M, Rali AS, Senussi MH, Bhatt AS, Hollenberg SM, Kini A, Menon V, Grubb KJ, Morrow DA, American College of Cardiology Critical Care Cardiology Section.   +13 more
europepmc   +2 more sources

The Burden and Trends of Degenerative Mitral Valve Disease at the Global, Regional, and National Levels From 1990 to 2021, With Projections to 2035

Global Heart
Background: Degenerative mitral valve disease (DMVD) is a significant contributor to the global burden of disease. This study aimed to estimate the prevalence, mortality, and disability-adjusted life years (DALYs) rates of DMVD at global, regional, and ...
Qiang Li, Yifan Yang, Zhi-Nan Lu, Xunan Guo, Xinmin Liu, Zhengming Jiang, Wenhui Wu, Chengqian Yin, Jianxin Li, Xiangfeng Lu, Guangyuan Song   +10 more
doaj   +1 more source

Contemporary Presentation and Management of Valvular Heart Disease: The EURObservational Research Programme Valvular Heart Disease II Survey. [PDF]

, 2019
Background: Valvular heart disease (VHD) is an important cause of mortality and morbidity and has been subject to important changes in management. The VHD II survey was designed by the EURObservational Research Programme of the European Society of ...
Bax, Jeroen J, Laroche, Cécile, Windecker, Stephan, Windecker, Stefan, Ruschitzka, Frank, Wendler, Olaf, Haude, Michael, Iung, Bernard, De Bonis, Michele, Piérard, Luc, Delgado, Victoria, Prendergast, Bernard, Bogachev-Prokophiev, Alexander, Price, Susanna, Ince, Hüseyin, EORP VHD II, Maggioni, Aldo, Popescu, Bogdan A, Vahanian, Alec, Rosenhek, Raphael, Tribouilloy, Christophe, Apor, Astrid, Hindricks, Gerhard, Evangelista, Arturo   +23 more
core   +2 more sources

First-in-human Results of the Novel Transcatheter Mitral Valve Repair System for Severe Mitral Regurgitation

Cardiology Discovery
Objective:. To evaluate the feasibility, safety, and effectiveness of a novel edge-to-edge mitral valve repair system (the NovoClasp system) in patients with severe mitral regurgitation. Methods:.
Zhi-Nan Lu, Yutong Ke, Yingnan Bian, Jing He, Wenhui Wu, Xinmin Liu, Yang Li, Ran Liu, Taiyang Luo, Xunan Guo, Guangyuan Song   +10 more
doaj   +1 more source

Interdisciplinary three-step strategy to treat aortic stenosis and coronary artery disease in a patient with end-stage chronic obstructive pulmonary disease [PDF]

, 2012
Background: Valvular aortic stenosis is a common disease in the elderly, often in multimorbid patients. It is often associated with coronary artery disease and peripheral artery disease.
Michel, Sebastian, Schmitz, Christoph, Kaczmarek, Ingo, Sodian, Ralf, Wolf, Manuel, Bigdeli, Amir Khosrow, Beiras Fernández, Andrés   +6 more
core   +1 more source