Results 91 to 100 of about 6,434,049 (298)

DUSP26 Regulated by YY1 Lactylation Couples Osteogenesis and Angiogenesis by Dephosphorylating PMPCB at Y141 and Activating Mitophagy in BMSCs

Advanced Science, EarlyView.
p300‐associated YY1 lactylation promotes DUSP26 expression in BMSCs. By regulating PMPCB phosphorylation and PINK1 processing, DUSP26 supports mitophagy, osteogenic differentiation, and pro‐angiogenic factor secretion. BMSC‐derived exosomes carrying a RUNX2 promoter‐driven DUSP26 plasmid favor osteogenic‐lineage transgene expression, partially ...
Yunpeng Lv, Feng Wu, Xiongjie Liang, Chong Liu, Wenhui Guo, Kejian Zhang, Jiawen Niu, Wenjie Jiang, Hongjian Xu, Anlong Jiang, Yang Zheng, Enming Yu, Xintao Wang, Jinglong Yan, Jingjun Xia, Chengchao Song   +15 more
wiley   +1 more source

Impact of valvular heart disease on activities of daily living of nonagenarians: the leiden 85-plus study a population based study

BMC Geriatrics, 2010
Background Data on the prevalence of valvular heart disease in very old individuals are scarce and based mostly on in-hospital series. In addition, the potential detrimental effect of valvular heart disease on the activities of daily living is unknown ...
Westendorp Rudi G, Blauw Gerard J, Gussekloo Jacobijn, Bax Jeroen J, Delgado Victoria, van Bemmel Thomas, Holman Eduard R   +6 more
doaj   +1 more source

Pathophysiology, Evaluation and Management of Valvular Heart Diseases, Vol. 2 : Developed from "Valves in the Heart of the Big Apple", New York, N.Y., May 2002 /

, 2004
Written by faculty members of the international symposium ‘Valves in the Heart of the Big Apple: Evaluation and Management of Valvular Heart Diseases’, this book is intended to complement and supplement the first volume, published in 2002.
Borer, J.S.
core  

Stroke‐Heart Syndrome: Mechanisms, Temporal Phenotypes, and Diagnostic Reasoning

Advanced Science, EarlyView.
Stroke‐heart syndrome describes new or worsened cardiac abnormalities after acute stroke. This Review defines its clinical boundaries, traces autonomic, inflammatory, endothelial, and supply‐demand mechanisms across time, and proposes provisional phenotypes that integrate lesion location, premorbid cardiac substrate, serial biomarkers ...
Fa Lin, Jian Lyu, Yanci Liu, Zhiyuan Feng, Jie Bao, Wenxiong Song, Bingcheng Zhu, Minghao Liu, Jionghao Xue, Jiadi Weng, Jiani Zhang, Jizong Zhao, Xiaolin Chen, Bin Dong   +13 more
wiley   +1 more source

Pregnancy and valvular heart disease

Saudi Medical Journal, 2003
OBJECTIVE: To review all cases of valvular heart disease during pregnancy in a regional Saudi-Arabian population between 1993-1997, determine its incidence, contributing factors and its effect on the outcome of pregnancy. METHODS: A retrospective study of 33,200 cases between 1993-1997 performed over a period of 5 years in the Department of Obstetrics ...
Shakeel A, Faiz, Abdulaziz A, Al-Meshari, Bengt G, Sporrong   +2 more
openaire   +2 more sources

Small Intestinal Bacterial Overgrowth Following Gastrointestinal Cancer Surgery: Current Evidence and Future Perspectives

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Small intestinal bacterial overgrowth (SIBO) has recently gained increasing attention as a potential cause of postoperative gastrointestinal symptoms following gastrointestinal cancer surgery. Surgical procedures can disrupt normal gastrointestinal physiology through anatomical reconstruction, impaired motility, reduced gastric acid secretion,
Toru Aoyama, Haruhiko Cho, Takaki Yoshikawa   +2 more
wiley   +1 more source

A Bioinspired Underwater Soft Robot for Active Intravesical Liquid Delivery and Mixing

Advanced Intelligent Systems, EarlyView.
A bioinspired underwater soft robot is reported that integrates an elastic strain energy‐driven soft robotic pump with a programmable flexible magnetic valve, enabling remotely controlled, programmable, and sustained liquid release and mixing. This functionality is enabled by the synergistic integration of elastic strain energy‐driven pumping and ...
Jacob Katona, Sage Bernstein, Boyang Xiao, Amie Zhang, Ellen Lu, Evan Ticknor, Jeffrey J. Tosoian, Xiaoguang Dong   +7 more
wiley   +1 more source

Rationale and design of SCOPE trial: a prospective, multicentre, open-label, randomised controlled trial to evaluate the overall efficacy and safety of a short-term anticoagulation strategy versus conventional single antiplatelet therapy in patients with severe aortic stenosis without indications for anticoagulation or dual antiplatelet therapy post-transcatheter aortic valve replacement

BMJ Open
Introduction While transcatheter aortic valve replacement (TAVR) has become a well-established standard of care for patients with symptomatic severe aortic stenosis, the optimal antithrombotic strategy post-TAVR remains a subject of debate, particularly ...
Yang Wang, Yan Li, Lihua Zhang, Ran Liu, Wei Wu, Yang Li, Huiping Zhang, Stuart Pocock, Xinmin Liu, Zhinan Lu, Taiyang Luo, Liang Guo, Fei Yuan, Yi-Da Tang, Yingxuan Zhu, Yunfeng Yan, Guangyuan Song, Zhengming Jiang, SCOPE Investigators   +18 more
doaj   +1 more source

Transition in Patients with Congenital Heart Disease in Germany: Results of a Nationwide Patient Survey

Frontiers in Pediatrics, 2017
BackgroundA growing number of adults with congenital heart disease (ACHD) pose a particular challenge for health care systems across the world. Upon turning into 18 years, under the German national health care system, ACHD patients are required to switch
Paul C. Helm, Paul C. Helm, Harald Kaemmerer, Günter Breithardt, Günter Breithardt, Elisabeth J. Sticker, Roland Keuchen, Rhoia Neidenbach, Gerhard-Paul Diller, Gerhard-Paul Diller, Oktay Tutarel, Ulrike M. M. Bauer, Ulrike M. M. Bauer, Ulrike M. M. Bauer   +13 more
doaj   +1 more source

Development of an Inchworm‐Like Dual‐Balloon‐Assisted Colonoscopic Robot Based on a Two‐Segment Extensible Continuum Section

Advanced Intelligent Systems, EarlyView.
This work presents an inchworm‐like dual‐balloon‐assisted colonoscopic robot (IDCR) based on a rod‐driven two‐segment continuum section. The IDCR enables the active straightening of the sigmoid colon through an inchworm‐like locomotion strategy, thereby avoiding loop formation.
Dezhi Song, Bohan Leng, Yi Liu, Xiangyang Yu, Chaoyang Shi   +4 more
wiley   +1 more source