Results 71 to 80 of about 6,434,049 (298)

Non‐Invasively Quantitative Raman Imaging for Calculation of Lymphatic Transport Kinetics of Micelles in Mice

Advanced Science, EarlyView.
Non‐invasively quantitative Raman imaging with stacking‐induced charge transfer‐enhanced Raman scattering (SICTERS) enables accurate measurement of concentrations and pharmacokinetic modeling of lymphatic transport of micelles in mice. This platform allows dynamic analysis of nanoparticle transport and underpins the design of effective lymph node ...
Yunlu Li, Hongzheng Lin, Sheng Yu, Yunhui Liao, Teng Huang, Zeyu Xiao, Wei Lu   +6 more
wiley   +1 more source

Evaluation of the safety and efficacy of a novel Anatomical classification and dUal anchoRing theory to Optimize the tavR strategy for pure severe Aortic regurgitation (AURORA): a prospective cohort study

BMC Cardiovascular Disorders, 2022
Background Success rate of transcatheter aortic valve replacement (TAVR) in aortic regurgitation (AR) patients is relatively low on account of the absence of calcified anchoring structures.
Jing Yao, Zhi-Nan Lu, Thomas Modine, Hasan Jilaihawi, Nicolo Piazza, Yi-Da Tang, Ji-Zhe Xu, Xiao-Ping Peng, Hai-Ping Wang, Chuan-Bao Li, Hui Chen, Chang-Fu Liu, Zheng-Ming Jiang, Jie Li, Fei-Cheng Yu, Ke Han, Sheng Wang, Hui Huang, Guang-Yuan Song   +18 more
doaj   +1 more source

Valvular Heart Disease in Pregnancy

Valvular heart disease is a common cause of peripartum cardiovascular morbidity and mortality. The hemodynamic changes of pregnancy and their impact on pre-existing valvular lesions are described in this paper.
Laith Alshawabkeh, Hilary Shapiro
core   +1 more source

Proteogenomic Profiling of Idiopathic Pulmonary Arterial Hypertension Identifies Sex‐Differential Proteins and Candidate Therapeutic Targets

Advanced Science, EarlyView.
An integrated proteogenomic analysis of 44,137 predominantly European‐ancestry UK Biobank participants aged 40–69 years identifies 12 robust proteins associated with idiopathic pulmonary arterial hypertension. These proteins define a high‐mortality molecular endotype, support early detection and mortality prediction, reveal sex‐differential proteomic ...
Xinjie Lin, Yangchang Zhang, Yang Pu, Duanke Liu, Tao Lei, Kai Ma, Qiyu He, Zheng Dou, Yuze Liu, Dengyuan Liu, Yinge He, Yanshang Wang, Xiaojiao Zheng, Yanbing Ma, Jianrong Zhou, Weiding Zhai, Binbin Su, Li Chen, Shoujun Li   +18 more
wiley   +1 more source

Frontiers in valvular heart disease [PDF]

European Heart Journal, 2016
Download the Issue @ a Glance podcast Subscribe to the EHJ Podcast ![Graphic][1] Valvular heart disease has experienced a remarkable revival of interest since the introduction of transarterial valve implantation (TAVI).1,2 After a difficult start with high-risk patients and initially significant complication rates, outcomes have remarkably ...
openaire   +3 more sources

Printing‐Assisted Integration of Thermal, Fluidic and Electrical Components in Implants for Focal Brain Cooling

Advanced Science, EarlyView.
Extrusion‐based 3D printing of silicones and discrete electronic components are combined to create cortical implants for rodents that integrate thermal neuromodulation and electrical recording. Linked to an autonomous auxiliary driver unit, the system enables rapid, stable and localized hypothermia alongside ECoG recording.
Spencer Ryan Moore, Naomi King, Aruã Clayton Da Silva, Clare Howarth, Jason Berwick, Thomas E. Paterson, Ivan R. Minev   +6 more
wiley   +1 more source

Rheumatic heart disease revisited: patterns of valvular involvement from a consecutive cohort in eastern Nepal [PDF]

, 2012
The burden of rheumatic heart disease (RHD) continues to be a major contributor to morbidity and premature death in poor and developing countries. We investigated patterns of valvular involvement in patients with RHD as observed in a large tertiary care ...
Bhandari, Rupak, Basnet, Sandeep, Shrestha, Nikesh Raj, Karki, Prahlad, Urban, Philip, Tiwari, Subikshya, Pilgrim, Thomas, Dhakal, Subodh Sagar   +7 more
core   +2 more sources

The Deubiquitinase UCHL1 Drives Susceptibility to Atrial Fibrillation by Stabilizing CaMKII‐δ

Advanced Science, EarlyView.
UCHL1 is highly upregulated in mice and patients with AF. UCHL1 directly binds to and removes K48‐linked polyubiquitin chains from CaMKII‐δ at K251 and enhances CaMKII‐δ stability, which activates RyR2, disrupts Ca2+ handling, and promotes AF. These findings establish UCHL1 as a critical regulator of CaMKII‐δ stability and AF‐related Ca2+ handling ...
Hai‐Lian Bi, Yu‐Hui Gu, Kai‐Wen Ren, Xiao‐Hong Yu, Yun‐Long Xia, Xiao‐Lei Yang, Hui‐Hua Li   +6 more
wiley   +1 more source

Surgical treatment of acquired valvular heart disease in elderly patients

, 2018
This article provides an overview of- studies on indications, surgery and outcomes of valvular heart disease surgery in elderly ...
Elmira N. Tukusheva, Kubatbek S. Urmanbetov, Tursunbek B. Kaliev, Sultanmurat Zhumabaev   +3 more
core   +2 more sources

Evaluating the Relationship between Rheumatic Valvular Heart Disease ‌and Coronary Artery Diseases in Patient with Stable Angina in Isfahan City, Iran

مجله دانشکده پزشکی اصفهان, 2018
Background: Rheumatic heart disease and coronary artery diseases (CAD) are two of main health problems in developing countries. Rheumatic valvular heart disease is less common than coronary artery diseases but it has its importance.
Faezeh Farhang, Zahra Alizadeh, Nizal Sarrafzadegan, Ali Pourmoghaddas, Ghasem Yadegarfar   +4 more
doaj   +1 more source