Results 171 to 180 of about 138,627 (294)

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai   +6 more
wiley   +1 more source

Vancomycin pharmacokinetics in patients with peritonitis on peritoneal dialysis

open access: green, 1983
B E Magera   +3 more
openalex   +1 more source

Intelligent peptide‐based nanomaterials for targeted antibacterial therapy: Design, properties and applications

open access: yesResponsive Materials, EarlyView.
This review comprehensively discusses intelligent peptide‐based nanomaterials from the design, mechanisms, properties, and applications, taking stimuli responsiveness as a starting point. Abstract Bacterial infections pose a major threat to human health as well as livestock production. Traditional antibiotics face significant limitations in the complex
Chenlong Zhou   +8 more
wiley   +1 more source

Micro‐ and nanomotors in biomedical applications

open access: yesResponsive Materials, EarlyView.
Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
wiley   +1 more source

A Case of Allergic Fungal Rhinosinusitis With Intradural Extension and Cerebritis

open access: yes
Otolaryngology–Head and Neck Surgery, EarlyView.
Nathaniel Oberholtzer   +3 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

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