Results 161 to 170 of about 182,488 (255)

Real‐world incidence and clinical characteristics of intraocular inflammation following intravitreal faricimab therapy: A safety study

Acta Ophthalmologica, EarlyView.
Abstract Purpose To estimate the real‐world incidence of intraocular inflammation (IOI) following intravitreal faricimab injections at a large, highly specialized tertiary centre. Methods Single‐centre, retrospective cohort study with chart review using an electronic injection database and electronic medical records from November 2023 to August 2024 ...
Miklos Schneider, Leyla Turan, Farah Arif, Jakob Bjerager, Oliver Niels Klefter, Carsten Faber, Yousif Subhi, Javad Nouri Hajari   +7 more
wiley   +1 more source

Emergence of a Novel, Phenotypically Difficult-to-Detect Vancomycin-Resistant Enterococcus faecium Clone (ST117/CT7799). [PDF]

Microbiologyopen
Forstner P, Uitz C, Dabernig-Heinz J, Wagner GE, Bender J, Fischer M, Siebenhofer D, Werner G, Busche T, Klages LJ, Rückert-Reed C, Steinmetz I, Dichtl K.   +12 more
europepmc   +1 more source

Antimicrobial Resistance in Children With Bloodstream Infections: A Population‐Based Study in Stockholm, Sweden

Acta Paediatrica, EarlyView.
ABSTRACT Aim We retrospectively evaluated trends in antimicrobial resistance (AMR) in paediatric bloodstream infections and assessed changes in antimicrobial prescription patterns over a 20‐year period. Methods We analysed positive blood cultures from children admitted with suspected serious infection between 1998 and 2018.
Joachim Luthander, Rutger Bennet, Per Nydert, Margareta Eriksson, Christian G. Giske, Anna Nilsson   +5 more
wiley   +1 more source

In vitro susceptibility of Cutibacterium acnes to dalbavancin: comparison between gradient test and the agar dilution reference method. [PDF]

J Antimicrob Chemother
Svensson S, Jacobsson S, Matuschek E, Söderquist B.   +3 more
europepmc   +1 more source

Equine vegetative endocarditis and vertebral osteomyelitis due to refractory Erysipelothrix rhusiopathiae infection

Equine Veterinary Education, EarlyView.
Summary Erysipelothrix rhusiopathiae was the causative agent of vegetative endocarditis and vertebral osteomyelitis in a 24‐year‐old Irish draught gelding that presented with prolonged history of intermittent pyrexia and tachycardia. Clinical investigations revealed persistently reduced neck mobility, tachydysrhythmia and episodic pyrexia up to 41°C ...
E. Kolovou, Z. Daobry, Â. J. F. Mendes, G. Weller, S. Radhakrishnan, M. S. I. Sajib, M. Fuentes, F. Zendri, T. Forde, W. Weir, J. Del‐Pozo, D. G. M. Sutton   +11 more
wiley   +1 more source

Vancomycin-variable enterococci as a silent reservoir of resistance: characterization of the first reported vancomycin-variable <i>Enterococcus faecium</i> isolate in Switzerland. [PDF]

Front Microbiol
Cherkaoui A, François P, Renzi G, Gaïa N, Bonetti EJ, Andrey DO, Schrenzel J.   +6 more
europepmc   +1 more source

Projected health‐service cost impact of dalbavancin consolidation therapy for Staphylococcus aureus bacteraemia in an Australian public health system

Internal Medicine Journal, EarlyView.
Abstract Background Management of Staphylococcus aureus bacteraemia (SAB) requires prolonged intravenous (IV) antibiotic therapy delivered in hospital or through Hospital in the Home (HITH), often requiring peripherally inserted central catheters (PICCs) and substantial healthcare resources.
Eli Dunn, Yolande Lindsay, Ian Marr, Fabian Chiong   +3 more
wiley   +1 more source

Comparative adjuvant therapy to reduce vancomycin-associated nephrotoxicity in an animal model. [PDF]

Antimicrob Agents Chemother
Xiao Y, Teran NS, Hudson CS, Nigo M, Tam VH.   +4 more
europepmc   +1 more source

Tigecycline combination therapy for fulminant Clostridioides difficile infection: an Australian experience

Internal Medicine Journal, EarlyView.
Abstract Background Recent European Society of Clinical Microbiology and Infection and Australasian Society of Infectious Diseases Clostridioides difficile infection (CDI) management guidelines endorse the addition of intravenous tigecycline in patients who are progressing to fulminant infection.
Emma Bishop, Tanya Ravipati, Steven Mileto, Eugene Athan, Dena Lyras, Ravindranath Tiruvoipati   +5 more
wiley   +1 more source

Immunometabolic Modulation by Low‐Dose Sodium Butyrate: PI3K/Akt/mTOR Signalling Orchestrates Macrophage Polarization to Protect Against Clostridioides difficile Colitis

Immunology, EarlyView.
Clostridioides difficile toxins TcdA and TcdB enter intestinal epithelial cells (IECs) via specific receptors, disrupt tight‐junction integrity and activate PI3K/Akt/mTOR signalling, promoting inflammasome assembly and IL‐1β release. Toxin‐induced IEC apoptosis further weakens the epithelial barrier.
Sisi Zhang, Zhou Jingxiang, Caixia Tan, Yuanyuan Xiao, Ju Zou, Biyue Tian, Anhua Wu, Chunhui Li   +7 more
wiley   +1 more source