Results 171 to 180 of about 182,488 (255)

Model-informed AUC-guided dosing for parenteral vancomycin in critically ill patients: impact on target attainment and renal safety - a pre-post intervention study. [PDF]

BMC Pharmacol Toxicol
Gundlach L, Kunkel M, Scherf-Clavel O, Surat G.   +3 more
europepmc   +1 more source

Temporal distribution of acute kidney injury–related hospitalizations after initiation of sodium–glucose cotransporter 2 inhibitors: A nationwide claims database analysis in older adults with an independent complementary single‐center eGFR analysis

Journal of Diabetes Investigation, EarlyView.
Among 190 older adults who experienced AKI‐related hospitalization after SGLT2 inhibitor initiation, 31.1% were hospitalized within 30 days. In an independent single‐center cohort, sustained early eGFR decline was associated with older age and use of one or two triple‐whammy‐related drug classes.
Kazuya Hiura, Ayana Tatsuno, Yamato Noto, Ryosuke Wakamatsu, Masayuki Sakunami, Ryu Kobayashi, Miki Yamashita   +6 more
wiley   +1 more source

Multisite Analysis of Vancomycin Concentration Predictions in a Bayesian Software in Adult and Pediatric Patients With and Without Acute Kidney Injury. [PDF]

Pharmacotherapy
Hughes MA, Pearson JC, Hughes JH.
europepmc   +1 more source

Cleanse, Perfuse, Retain (CPR) Protocol for Management of Postoperative Infections With d‐PTFE Membranes: Clinical Reports of Three Cases

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective Postoperative infection is a serious complication of bone augmentation procedures, potentially resulting in graft failure, basal bone resorption, and spread of infection to adjacent anatomic spaces. This paper introduces the CPR (Cleanse, Perfuse, and Retain) protocol and illustrates its clinical application in the management of low‐
Istvan A. Urban, Zhaozhao Chen, Hom‐Lay Wang   +2 more
wiley   +1 more source

RefSeq-corrected transcriptomic and RNA-interaction integration maps medium-associated vancomycin response rewiring in <i>Staphylococcus aureus</i>. [PDF]

Front Microbiol
Li Z, Liu H, Yang B, Liu S, Li Z, Yu S.
europepmc   +1 more source

Postelectroacupuncture Fecal Microbiota Transplantation (post‐EA FMT) Regulates Gastrointestinal Hormones in Functional Dyspepsia Rats Is Associated With Modulation of the Intestinal Microbiota‐Bile Acid Metabolic Pathway

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background Electroacupuncture (EA) reshapes intestinal flora; whether post‐EA fecal microbiota transplantation (post‐EA FMT) regulates gastrointestinal hormones via the gut microbiota–bile acid (BA) pathway remains unclear. Methods Sham EA (SEA) served as control. Gastrointestinal hormones/motility were assessed post‐EA.
Yong‐Li Han, Dong‐Fang Shang, Juli Tang, Dong‐Dong Yu, Liang‐Yu Zhang, Jing Zhou, Qing‐Bo Wang   +6 more
wiley   +1 more source

Discrepancies in Vancomycin Clearance Estimation Among Renal Function Models in Patients With Low Serum Creatinine Levels: A Pilot Study. [PDF]

Basic Clin Pharmacol Toxicol
Nakano Y, Hirai T, Sogawa R, Hasuwa H, Shimanoe C.   +4 more
europepmc   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source

Pharmacokinetic, Pharmacodynamic, and Clinical Outcomes of Vancomycin and β-Lactam Antibiotics in Adults With Augmented Renal Clearance: A Systematic Review. [PDF]

Cureus
Asiri M, Alharbi S, Alharbi M, Alharbi G.   +3 more
europepmc   +1 more source

The ComEA/ComEC Operon is Critical for Nitrosative Stress Tolerance by an Oral Commensal

Molecular Oral Microbiology, EarlyView.
ABSTRACT Oral commensal streptococci play a large role in mediating microbial homeostasis. Our prior work has demonstrated that hydrogen peroxide (H2O2) produced by oral commensal streptococci can react with salivary nitrite (NO2) and generate peroxynitrite (ONOO−), a potent antimicrobial.
Sara E. Edmonds, Hernan Grenett, Priscilla Grenett, Jessica A. Scoffield   +3 more
wiley   +1 more source