Thermal defrosting limits desublimator efficiency in freeze‐drying. This review and case study compares thermal versus mechanical regeneration, links frost properties and external heat transfer to energy demand, and summarizes pilot‐scale scraping results enabling single‐unit, continuous lyophilization.
Moritz Krummenacher +3 more
wiley +1 more source
Deciphering the binding strength of oil matrix through molecularly resolved release energy analysis using thermal slicing ramped pyrolysis GC-MS. [PDF]
Lu K, Xue J, Liu Z.
europepmc +1 more source
Communication: An approach for a holistic evaluation of distillation processes with mechanical vapor recompression combining an initial energy potential analysis, shortcut methods for the compressor and reboiler design, and the determination of economic and ecological performance parameters is presented.
Katharina Jasch +4 more
wiley +1 more source
Measurement and modeling of rizatriptan in supercritical CO<sub>2</sub> for pharmaceutical processing. [PDF]
Bawazeer S.
europepmc +1 more source
AutoVap: An Interactive Machine Learning Tool for Predicting the Standard Enthalpy of Vaporization
AutoVap (https://autovap.jfcaetano.com) is a web app that predicts ΔvapHm° from SMILES using an RDKit‐based ML model, giving accurate, interpretable results with uncertainty across diverse molecules. ABSTRACT This communication introduces AutoVap (https://autovap.jfcaetano.com), an interactive web application for predicting the standard molar enthalpy ...
José Ferraz‐Caetano
wiley +1 more source
Machine Learning-Guided Prediction of Formulation Performance in Inhalable Ciprofloxacin-Bile Acid Dispersions with Antimicrobial and Toxicity Evaluation. [PDF]
Bahjat TZ +10 more
europepmc +1 more source
Optimal model‐based design of experiments for parameter precision: Supercritical extraction case
Abstract This study investigates the process of chamomile oil extraction from flowers. A parameter‐distributed model consisting of a set of partial differential equations is used to describe the governing mass transfer phenomena in a cylindrical packed bed with solid chamomile particles under supercritical conditions using carbon dioxide as a solvent ...
Oliwer Sliczniuk, Pekka Oinas
wiley +1 more source
Multi criterion decision making analysis of hematologic cancer drugs via topological indices and physicochemical properties. [PDF]
Huang L +5 more
europepmc +1 more source
A‐optimal model‐based design of experiments for processes with uncertain inputs
Abstract Model‐based design of experiments (MBDoE) techniques are tools for selecting experimental conditions that enable accurate parameter estimation for mechanistic models. Most MBDoE approaches assume that the selected experimental conditions will be implemented perfectly, without uncertainties in the independent variables.
Bright Ofori +3 more
wiley +1 more source
Continuous tuning of ejector parameters via zeotropic component migration for optimising high-temperature heat pump. [PDF]
Li Z, Liang Y, Zhu Y, Yao S, Yu Z.
europepmc +1 more source

