Drug Delivery in Photodynamic Therapy [PDF]
Pharmaceutics, 2023 Photodynamic therapy (PDT) has gained prominence as a non-invasive and selective treatment option for solid tumors and non-oncological diseases [...]
Francesca Moret, Greta Varchi
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SMYD3 Modulates AMPK-mTOR Signaling Balance in Cancer Cell Response to DNA Damage [PDF]
Cells, 2023 Cells respond to DNA damage by activating a complex array of signaling networks, which include the AMPK and mTOR pathways. After DNA double-strand breakage, ATM, a core component of the DNA repair system, activates the AMPK-TSC2 pathway, leading to the ...
Martina Lepore Signorile +12 more
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SMYD3 Modulates the HGF/MET Signaling Pathway in Gastric Cancer [PDF]
Cells, 2023 Gastric cancer (GC) is the third most deadly cancer worldwide. Considerable efforts have been made to find targetable drivers in order to improve patient outcomes.
Katia De Marco +11 more
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Pheophorbide A and Paclitaxel Bioresponsive Nanoparticles as Double-Punch Platform for Cancer Therapy [PDF]
Pharmaceutics, 2021 Cancer therapy is still a challenging issue. To address this, the combination of anticancer drugs with other therapeutic modalities, such as light-triggered therapies, has emerged as a promising approach, primarily when both active ingredients are ...
Francesca Moret +8 more
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Two Beats One: Osteosarcoma Therapy with Light-Activated and Chemo-Releasing Keratin Nanoformulation in a Preclinical Mouse Model [PDF]
Pharmaceutics, 2022 Osteosarcoma treatment is moving towards more effective combination therapies. Nevertheless, these approaches present distinctive challenges that can complicate the clinical translation, such as increased toxicity and multi-drug resistance.
Elisa Martella +14 more
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Poemas de mármore: Michelangelo escultor e poeta nas Lezioni de Benedetto Varchi
Revista Brasileira De Historia, 1998 Em 1547, o filósofo florentino Benedetto Varchi pronunciou uma série de conferências, chamadas de Lezioni, sobre o soneto de Michelangelo "Non há l'ottimo artista alcun concetto" e sobre a questão da superioridade da escultura, da pintura ou da poesia na
Luciano Migliaccio
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Benedetto Varchi et Charles Quint
Cahiers d’Études Romanes, 2019 Charles Quint maître du monde est le titre du livre que Juan Carlos D’Amico consacre à l’empereur du Saint Empire. Notre propos s’intéresse à cet éminent personnage à travers le regard d’un historiographe de la Renaissance italienne, Benedetto Varchi ...
Théa Picquet
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Mesenchymal stromal cells mediated delivery of photoactive nanoparticles inhibits osteosarcoma growth in vitro and in a murine in vivo ectopic model [PDF]
Journal of Experimental & Clinical Cancer Research, 2020 Background Osteosarcoma (OS) is an aggressive malignant neoplasm that still suffers from poor prognosis in the case of distal metastases or occurrence of multi-drug resistance.
Stefania Lenna +14 more
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Light-Induced Therapies for Prostate Cancer Treatment [PDF]
Frontiers in Chemistry, 2019 Prostate cancer (PC) is one of the most widespread tumors affecting the urinary system and the fifth-leading cause from cancer death in men worldwide.
Claudia Ferroni +5 more
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HSA-nanobinders crafted from bioresponsive prodrugs for combined cancer chemoimmunotherapy–an in vitro exploration [PDF]
Frontiers in ChemistryIntroduction: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer still lacking effective treatment options. Chemotherapy in combination with immunotherapy can restrict tumor progression and repolarize the tumor ...
Matilde Tubertini +14 more
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