Results 11 to 20 of about 5,778 (178)

Light-Induced Therapies for Prostate Cancer Treatment [PDF]

Frontiers in Chemistry, 2019
Prostate cancer (PC) is one of the most widespread tumors affecting the urinary system and the fifth-leading cause from cancer death in men worldwide.
Claudia Ferroni, Alberto Del Rio, Alberto Del Rio, Cecilia Martini, Elisabetta Manoni, Greta Varchi   +5 more
doaj   +2 more sources

Mesenchymal stromal cells mediated delivery of photoactive nanoparticles inhibits osteosarcoma growth in vitro and in a murine in vivo ectopic model [PDF]

Journal of Experimental & Clinical Cancer Research, 2020
Background Osteosarcoma (OS) is an aggressive malignant neoplasm that still suffers from poor prognosis in the case of distal metastases or occurrence of multi-drug resistance.
Stefania Lenna, Chiara Bellotti, Serena Duchi, Elisa Martella, Marta Columbaro, Barbara Dozza, Marco Ballestri, Andrea Guerrini, Giovanna Sotgiu, Tommaso Frisoni, Luca Cevolani, Greta Varchi, Mauro Ferrari, Davide Maria Donati, Enrico Lucarelli   +14 more
doaj   +2 more sources

HSA-nanobinders crafted from bioresponsive prodrugs for combined cancer chemoimmunotherapy–an in vitro exploration [PDF]

Frontiers in Chemistry
Introduction: Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer still lacking effective treatment options. Chemotherapy in combination with immunotherapy can restrict tumor progression and repolarize the tumor ...
Matilde Tubertini, Matilde Tubertini, Luca Menilli, Celeste Milani, Cecilia Martini, Maria Luisa Navacchia, Marta Nugnes, Manuela Bartolini, Marina Naldi, Daniele Tedesco, Elisa Martella, Andrea Guerrini, Claudia Ferroni, Francesca Moret, Greta Varchi   +14 more
doaj   +2 more sources

Benedetto Varchi on the Soul: Vernacular Aristotelianism between Reason and Faith [PDF]

Journal of the History of Ideas, 2015
In this paper, I wish to present the first full-fledged investigation of Benedetto Varchi’s manuscript writings on psychology, which show the depth of his familiarity with philosophy and his originality as a thinker. In particular, I wish to show that Varchi was not an Averroist.
Marco Sgarbi
exaly   +5 more sources

Anticancer activity of paclitaxel-loaded keratin nanoparticles in two-dimensional and perfused three-dimensional breast cancer models [PDF]

International Journal of Nanomedicine, 2018
Federica Foglietta,1 Giulio C Spagnoli,2,3 Manuele Giuseppe Muraro,2 Marco Ballestri,4 Andrea Guerrini,4 Claudia Ferroni,4 Annalisa Aluigi,4 Giovanna Sotgiu,4 Greta Varchi4 1Department of Drug Science & Technology, University of Torino, Torino ...
Foglietta F, Spagnoli GC, Muraro MG, Ballestri M, Guerrini A, Ferroni C, Aluigi A, Sotgiu G, Varchi G   +8 more
doaj   +2 more sources

Effect of small molecules modulating androgen receptor (SARMs) in human prostate cancer models. [PDF]

PLoS ONE, 2013
The management of hormone-refractory prostate cancer represents a major challenge in the therapy of this tumor, and identification of novel androgen receptor antagonists is needed to render treatment more effective.
Anna Tesei, Carlo Leonetti, Marzia Di Donato, Elisa Gabucci, Manuela Porru, Greta Varchi, Andrea Guerrini, Dino Amadori, Chiara Arienti, Sara Pignatta, Giulia Paganelli, Michele Caraglia, Gabriella Castoria, Wainer Zoli   +13 more
doaj   +2 more sources

The novel SMYD3 inhibitor EM127 impairs DNA repair response to chemotherapy-induced DNA damage and reverses cancer chemoresistance [PDF]

Journal of Experimental & Clinical Cancer Research
Background SMYD3 has been found implicated in cancer progression. Its overexpression correlates with cancer growth and invasion, especially in gastrointestinal tumors.
Paola Sanese, Katia De Marco, Martina Lepore Signorile, Francesca La Rocca, Giovanna Forte, Marialaura Latrofa, Candida Fasano, Vittoria Disciglio, Elisabetta Di Nicola, Antonino Pantaleo, Giusy Bianco, Vito Spilotro, Claudia Ferroni, Matilde Tubertini, Nicoletta Labarile, Lucia De Marinis, Raffaele Armentano, Gianluigi Gigante, Valerio Lantone, Giuliano Lantone, Marina Naldi, Manuela Bartolini, Greta Varchi, Alberto Del Rio, Valentina Grossi, Cristiano Simone   +25 more
doaj   +2 more sources

Tailoring a novel colorectal cancer stem cell-targeted therapy by inhibiting the SMYD3/c-MYC axis [PDF]

Signal Transduction and Targeted Therapy
Cancer stem cells (CSCs) are responsible for colorectal cancer (CRC) chemoresistance, recurrence, and metastasis. Therefore, identifying molecular stemness targets that are involved in tumor growth is crucial for effective treatment.
Martina Lepore Signorile, Elisabetta Di Nicola, Giovanna Forte, Paola Sanese, Candida Fasano, Vittoria Disciglio, Katia De Marco, Marialaura Latrofa, Loris De Cecco, Marica Ficorilli, Marta Lucchetta, Erica Torchia, Chiara Dossena, Giusy Bianco, Vito Spilotro, Claudia Ferroni, Nicoletta Labarile, Raffaele Armentano, Francesco Albano, Anna Mestice, Gianluigi Gigante, Valerio Lantone, Giuliano Lantone, Leonardo Vincenti, Alberto Del Rio, Greta Varchi, Valentina Grossi, Cristiano Simone   +27 more
doaj   +2 more sources

Editorial: Small molecules and smart drug delivery systems for combination cancer immunotherapy [PDF]

Frontiers in Chemistry
Claudia Ferroni, Greta Varchi
doaj   +2 more sources

Polymeric nanoparticles enhance the sonodynamic activity of meso-tetrakis (4-sulfonatophenyl) porphyrin in an in vitro neuroblastoma model [PDF]

International Journal of Nanomedicine, 2013
Roberto Canaparo,1,* Greta Varchi,2,* Marco Ballestri,2 Federica Foglietta,1 Giovanna Sotgiu,2 Andrea Guerrini,2 Andrea Francovich,3 Pierluigi Civera,3 Roberto Frairia,4 Loredana Serpe1 1Department of Drug Science and Technology, University of Torino ...
Canaparo R, Varchi G, Ballestri M, Foglietta F, Sotgiu G, Guerrini A, Francovich A, Civera P, Frairia R, Serpe L   +9 more
doaj   +2 more sources