Results 101 to 110 of about 20,263 (262)

Varenicline Targets the Reinforcing-Enhancing Effect of Nicotine on Its Associated Salient Cue During Nicotine Self-administration in the Rat

Frontiers in Behavioral Neuroscience, 2019
Nicotine is acknowledged as the key addictive compound of tobacco. Varenicline (Champix® or Chantix®), mainly acting as a partial agonist at the α4β2 nicotinic receptor, is an approved smoking cessation pharmacotherapy, although with efficacy limited to ...
Vernon Garcia-Rivas, Vernon Garcia-Rivas, Jean-François Fiancette, Jean-François Fiancette, Nazzareno Cannella, Nazzareno Cannella, Maria Carbo-Gas, Maria Carbo-Gas, Prisca Renault, Prisca Renault, Jessica Tostain, Jessica Tostain, Véronique Deroche-Gamonet, Véronique Deroche-Gamonet   +13 more
doaj   +1 more source

Risk Factors for Cardiovascular and Metabolic Disease: Integrating Traditional and Novel Paradigms

iNew Medicine, Volume 1, Issue 1, December 2025.
ABSTRACT Cardiovascular and metabolic diseases (CVMD), encompassing atherosclerotic cardiovascular disease (ASCVD), heart failure, obesity, type 2 diabetes mellitus (T2DM), and metabolic dysfunction‐associated steatotic liver disease (MASLD), remain the leading global cause of morbidity and mortality.
Zhihua Wang, Shuo Chen, Suowen Xu, Jianping Weng   +3 more
wiley   +1 more source

Genetic Variant in CHRNA5 and Response to Varenicline and Combination Nicotine Replacement in a Randomized Placebo‐Controlled Trial

Clinical pharmacology and therapy, 2020
It is unclear if genetic variants affect smoking cessation treatment response. This study tested whether variants in the cholinergic receptor nicotinic alpha 5 subunit (CHRNA5) predict response to smoking cessation medication by directly comparing the ...
Li-Shiun Chen, T. Baker, J. Miller, M. Bray, Nina Smock, Jingling Chen, Faith Stoneking, R. Culverhouse, N. Saccone, Christopher I. Amos, R. Carney, D. Jorenby, L. Bierut   +12 more
semanticscholar   +1 more source

Smoking Cessation Agents and Suicide [PDF]

, 2009
The risk is uncertain, so patients should make an informed ...
Lavigne, Jill E
core   +2 more sources

Smoking cessation in severe mental ill health : what works? an updated systematic review and meta-analysis [PDF]

, 2017
BACKGROUND: People with severe mental ill health are more likely to smoke than those in the general population. It is therefore important that effective smoking cessation strategies are used to help people with severe mental ill health to stop smoking ...
A Baker, A Baker, AE Evins, AE Evins, AE Evins, AE Evins, AH Weinberger, AL Baker, B O'Brien, BS Wu, C Bullen, C McDonald, E Ratschen, E Weiner, E Weiner, Emily Peckham, Garry Tew, GW Dalack, HK Chen, J Hartmann-Boyce, JM Williams, JM Williams, JM Williams, JW Tidey, KN Chengappa, KR Fontaine, L Banham, Liz Cook, ML Steinberg, ML Steinberg, Q Wu, RC Smith, RM Anthenelli, S Brown, S Fatemi, S Gilbody, Sally Brabyn, SE Adkison, Simon Gilbody, SM Gallagher, TP George, TP George, TP George, VC Wing   +43 more
core   +1 more source

Trends, timing, and predictors of alcohol use disorder treatment among US adult cancer survivors

Journal of Internal Medicine, Volume 298, Issue 6, Page 670-685, December 2025.
Abstract Background Little is known about the initiation of alcohol use disorder (AUD) treatments among cancer survivors, despite the unique harms that unhealthy alcohol use may have on this population. We assessed patterns, timing, and predictors of AUD treatment among cancer survivors.
Jyun‐Heng Lai, Anton L. V. Avanceña, Minh H. K. Nguyen, Corwin M. Zigler, Mary M. Velasquez, Christopher R. Frei, Michael Pignone   +6 more
wiley   +1 more source

Using the Social-Local-Mobile App for Smoking Cessation in the SmokeFreeBrain Project: Protocol for a Randomized Controlled Trial [PDF]

, 2018
Background: Smoking is considered the main cause of preventable illness and early deaths worldwide. The treatment usually prescribed to people who wish to quit smoking is a multidisciplinary intervention, combining both psychological advice and ...
Bamidis, Panagiotis D., Carrasco Hernández, Laura, Civit Balcells, Antón, Fernández Luque, Luis, Hors Fraile, Santiago, Jódar Sánchez, Francisco, Mesa González, Marco Antonio, Moreno Conde, Jesús, Núñez Benjumea, Francisco José, Ortega Ruiz, Francisco, Parra Calderón, Carlos Luis   +10 more
core   +3 more sources

Does e‐cigarette nicotine strength influence substitution for combustible cigarettes?

Journal of the Experimental Analysis of Behavior, Volume 124, Issue 3, November 2025.
Abstract Using the Experimental Tobacco Marketplace, we examined the effects of e‐liquid freebase nicotine strength (3–24 mg/mL) and e‐liquid price (US$0.25–$1.00/mL) on behavioral economic substitution for cigarettes in dual cigarette/e‐cigarette (n = 41) and exclusive cigarette (n = 40) users.
Jeffrey S. Stein, Allison N. Tegge, Jeremiah M. Brown, Kelsey M. Curran, Warren K. Bickel   +4 more
wiley   +1 more source

Evaluation of the cardiovascular effects of varenicline in rats

Drug Design, Development and Therapy, 2015
Engin Burak Selçuk,1 Meltem Sungu,2 Hakan Parlakpinar,3 Necip Ermiş,4 Elif Taslıdere,5 Nigar Vardı,5 Murat Yalçinsoy,6 Mustafa Sagır,3 Alaaddin Polat,7 Mehmet Karatas,8 Burcu Kayhan-Tetik11Department of Family Medicine, 2Inonu University ...
Selçuk EB, Sungu M, Parlakpinar H, Ermiş N, Taslıdere E, Vardı N, Yalçınsoy M, Sagır M, Polat A, Karatas M, Kayhan-Tetik B   +10 more
doaj  

Economic evaluation of smoking cessation in Ontario's regional cancer programs. [PDF]

, 2018
Quitting smoking after a diagnosis of cancer results in greater response to treatment and decreased risk of disease recurrence and second primary cancers.
Cameron, Erin, Chan, Kelvin, Djalalov, Sandjar, Evans, William, Hoch, Jeffrey S, Isaranuwatchai, Wanrudee, Masucci, Lisa, Mittmann, Nicole, Peter, Alice, Rabeneck, Linda, Truscott, Rebecca   +10 more
core   +1 more source