Results 81 to 90 of about 10,641 (185)

Varenicline for cognitive impairment in people with schizophrenia: systematic review and meta-analysis

, 2019
Background People with schizophrenia frequently have cognitive dysfunction, which does not respond to pharmacological interventions. Varenicline has been identified as a potential treatment option for nicotinic receptor dysfunction with a potential to ...
Melo, Catarina Drumonde, De Monte, Veronica, Gore-Jones, Victoria, Shah, S, Gore-Jones, V, Rossell, Susan L., Benson, Catherine, Siskind, Dan, Shah, Shelukumar, Rossell, SL, Siskind, D, Tanzer, Timothy, Kisely, Steve, Kisely, S, Dark, Frances, Dark, F, Melo, CD, Tanzer, T, Benson, C, De Monte, V   +19 more
core   +1 more source

Addressing varenicline adherence through repackaging in a dose administration aid

, 2017
Aaron D Drovandi, Sherryl G Robertson, Bunmi S Malau-Aduli, Peta Ann Teague, Beverley D Glass College of Medicine and Dentistry, James Cook University, Townsville, QLD, Australia Background: Ensuring adherence to prescribed smoking ...
Drovandi AD, Malau-Aduli BS, Teague PA, Glass BD, Robertson SG   +4 more
core  

The data set describing cognitive performance after varenicline administration in a 3-choice serial reaction time task in rats

Data in Brief, 2017
The data shows attentional function, impulsivity, motivation, motor function, and motor activity in rats treated with varenicline, a stop-smoking aid.
Yu Ohmura, Hitomi Sasamori, Iku Tsutsui-Kimura, Takeshi Izumi, Takayuki Yoshida, Mitsuhiro Yoshioka   +5 more
doaj   +1 more source

Combination therapy of varenicline and bupropion in smoking cessation: A meta-analysis of the randomized controlled trials

Comprehensive Psychiatry, 2019
Background: The effects of the combination therapy of varenicline and bupropion in smoking cessation are still controversial. Methods: Databases including PubMed, EMBASE, Cochrane Library and Web of Science were scanned without time and language ...
Zhaoshuang Zhong, Shijie Zhao, Yan Zhao, Shuyue Xia   +3 more
doaj   +1 more source

Efficacy of Varenicline in Smoking Cessation—A Systematic Review and Meta-analysis

Journal of Indian Academy of Oral Medicine and Radiology
Background: Tobacco use is a leading cause of morbidity and mortality. Smoking cessation significantly reduces related health risks. Varenicline, a partial nicotine receptor agonist, may aid cessation by reducing cigarette consumption and dependence ...
Reethu Ravichandiran, Venkatesh Jayaraman, Ramasamy Sarvathikari, Ramya Kalyanasundaram, Vijayalakshmi Lakshmanan, Sakthivel Sambasivam   +5 more
doaj   +1 more source

A cost-effectiveness analysis of varenicline for smoking cessation using data from the EAGLES trial

, 2018
Christine L Baker,1 Guilhem Pietri2 1Pfizer Inc., New York, NY, USA; 2Data Pyxis Ltd., St Albans, UK Background: The cost-effectiveness of varenicline has been demonstrated in the US health care setting using the Benefits of Smoking Cessation on Outcomes
Baker CL, Pietri G
core  

Hypotension and bradycardia following varenicline overdose [Abstract]

, 2009
Objective: To report a case of symptomatic varenicline overdose in an adult. Case report: Varenicline is a new drug for smoking cessation. It is both a partial agonist and antagonist to the nicotine receptor.
Jones, S. S. D., Thompson, John Paul, Wood, K. L.   +2 more
core   +1 more source

Preclinical pharmacology, efficacy, and safety of varenicline in smoking cessation and clinical utility in high risk patients

, 2010
Zheng-Xiong XiNational Institute on Drug Abuse, Intramural Research Program, Baltimore, MD, USAAbstract: Smoking is still the most prominent cause of preventable premature death in the United States and an increasing cause of morbidity and mortality ...
Zheng-Xiong Xi
core  

2532

Journal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: The central goal is to predict the metabolites of varenicline and predictively evaluate their propensities for eliciting an increased binding effect in the brain.
Keeshaloy Thompson, Milton Brown
doaj   +1 more source

Fatality following a suicidal overdose with varenicline

, 2013
The smoking cessation agent varenicline acts as a partial agonist on alpha(4)beta(2) nicotinic acetylcholine receptors. Although debated, several reports have linked varenicline therapy to an increased risk of suicidal thoughts and/or suicide.
De Letter, Els, Piette, Michel, Lambert, Willy, Stove, Christophe   +3 more
core   +1 more source