Results 61 to 70 of about 11,119 (184)

2026 Asia Pacific Heart Rhythm Society (APHRS) Guidelines (Part IV) on Comprehensive Lifestyle Risk Factor and Comorbidity Management in Atrial Fibrillation

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
ABSTRACT Atrial fibrillation (AF) is closely associated with comorbidities and lifestyle factors that influence the development, progression, and outcomes. Here the focus is on guidelines for the systematic management of hypertension, heart failure, coronary and structural heart disease, diabetes, dyslipidemia, cerebrovascular disease, obesity, chronic
Eue‐Keun Choi, Melissa E. Middeldorp, Hyo‐Jeong Ahn, Jonathan P. Ariyaratnam, Adrian D. Elliott, Chung‐Lieh Hung, Hee Tae Yu, Gautam Sharma, Ningjian Wang, Takanori Yamaguchi, Minglong Chen, Boyoung Joung, Rungroj Krittayaphong, Kyoko Soejima, Gregory Y. H. Lip, Hui‐Nam Pak, Tze‐Fan Chao   +16 more
wiley   +1 more source

Efficacy of Varenicline in Patients With Severe Alcohol Dependence: A Pilot Double-Blind Randomized and Controlled Study. [PDF]

, 2019
Purpose/Background: Varenicline has proven its efficacy in the treatment of nicotine dependence, and there is also evidence that it could be helpful in the treatment of alcohol dependence.
Pfeifer, Philippe, Christoph Fehr, Fehr, Christoph, Philippe Pfeifer   +3 more
core   +2 more sources

Electronic Cigarettes Versus Varenicline for Smoking Cessation: A Systematic Review and Meta-analysis of in-person Support Augmentation Strategies

Indian Journal of Community Medicine
Tobacco smoking is a global health crisis, causing over 8 million deaths annually, including 1.3 million in India. The rise of electronic cigarettes (e-cigarettes) has raised questions about their effectiveness compared to traditional aids like ...
Aruhi Sinha, Milind Wasnik, Ramakrishna Chevvuri   +2 more
doaj   +1 more source

Brain Penetrant Calcium Channel Blockers Were Not Associated With Reduced Alcohol Consumption: Converging Results From Two Large Independent Cohort Studies Using Electronic Health Records

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 10, October 2026.
ABSTRACT Purpose Alcohol use disorder (AUD) remains a major public health problem, with few effective treatments. L‐type calcium channel blockers (LTCCBs) have genetic and preclinical support as potential treatments for AUD. Methods We evaluated whether brain penetrant (BP)‐LTCCBs are associated with reduced alcohol consumption in two preregistered ...
Christopher T. Rentsch, Vanessa A. Palzes, Mingjian Shi, Michael R. Setzer, Samantha G. Malone, Andrea H. Kline‐Simon, Emma L. Winterlind, Lorenzo Leggio, Vincent Lo Re III, David A. Fiellin, John Tazare, Mehdi Farokhnia, Stacy Sterling, Henry R. Kranzler, Joshua C. Gray   +14 more
wiley   +1 more source

Varenicline as a smoking cessation aid in a Greek population: a subanalysis of an observational study [PDF]

, 2012
Background: Greece has the highest proportion of smokers in the European Union with 42% of Greeks admitting that they smoke, based on a 2009 survey.
Paraskevi Pataka, Raju, S., Pataka, P. A., Gratziou, C., Georgia D Sykara, Sunil Raju, Konstantinos I. Gourgoulianis, Konstantinos Gourgoulianis, Christina Gratziou, Sykara, G. D., Paraskevi Argyropoulou Pataka, Michael Messig, Messig, M., Georgia D. Sykara, Gourgoulianis, K.   +14 more
core   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, Volume 53, Issue 10, Page 887-892, October 2026.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Varenicline Targets the Reinforcing-Enhancing Effect of Nicotine on Its Associated Salient Cue During Nicotine Self-administration in the Rat

Frontiers in Behavioral Neuroscience, 2019
Nicotine is acknowledged as the key addictive compound of tobacco. Varenicline (Champix® or Chantix®), mainly acting as a partial agonist at the α4β2 nicotinic receptor, is an approved smoking cessation pharmacotherapy, although with efficacy limited to ...
Vernon Garcia-Rivas, Vernon Garcia-Rivas, Jean-François Fiancette, Jean-François Fiancette, Nazzareno Cannella, Nazzareno Cannella, Maria Carbo-Gas, Maria Carbo-Gas, Prisca Renault, Prisca Renault, Jessica Tostain, Jessica Tostain, Véronique Deroche-Gamonet, Véronique Deroche-Gamonet   +13 more
doaj   +1 more source

Smoking cessation therapy with varenicline

, 2008
Uma M Mohanasundaram, Rajinder Chitkara, Ganesh KrishnaDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Stanford University School of Medicine, CA, USAAbstract: Smoking cessation is the only available intervention proven to halt ...
Ganesh Krishna, Rajinder Chitkara, Uma M Mohanasundaram   +2 more
core  

Crosstalk Between Cortical Plasticity and Peripheral Nervous Injury: Insights, Mechanisms, and Future Directions

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Peripheral nerve injury induces dynamic cortical plasticity, driven by molecular mechanisms such as BDNF and neurotransmitter systems. This review synthesizes subtype‐specific plasticity patterns: compressive injuries trigger rapid reorganization, while metabolic neuropathies lead to maladaptive changes.
Cong Cheng, Dong Gao, Yaojie Shen, Xi Wang, Junxi Dai, Yaoxian Xiang, Zongyuan Jiang, Zongqi You, Junjian Jiang   +8 more
wiley   +1 more source

Varenicline may trigger severe hypoglycaemia in Type 1 diabetes

, 2008
Background Varenicline is a new drug indicated for smoking cessation. It has primarily been investigated in healthy adults. The commonest side-effects are nausea, headache, sleep disturbance, constipation, flatulence and vomiting.
Thorsteinsson, B., Pedersen-Bjergaard, U., Kristensen, P.L.   +2 more
core   +1 more source