Results 11 to 20 of about 19,420 (250)
Varenicline for Smoking Cessation [PDF]
Expert Review of Neurotherapeutics, 2007 Varenicline is a selective alpha(4)beta(2) nicotinic acetylcholine receptor partial agonist and the first non-nicotine-containing medication developed with the sole purpose of treating nicotine addiction. To date, four published clinical trials have demonstrated the efficacy and safety of varenicline for smoking cessation in healthy adults who were ...
Jon O. Ebbert, Eric G. Tangalos
+16 more sources
Varenicline: quantifying the risk [PDF]
Canadian Medical Association Journal, 2011 We agree that there is a lack of clarity in Singh and colleagues’ article; it is very difficult for readers to follow how the various assumptions and extrapolations have been made.[1][1] The rather alarming figure of a 72% increase in serious cardiovascular events has been picked up by the ...
Edward N. Squire
+23 more sources
Varenicline for Tobacco Dependence [PDF]
New England Journal of Medicine, 2008 A 57-year-old man with a 60-pack-year history visits his primary care provider because he wants to quit smoking. He has a history of stable coronary artery disease, peripheral vascular disease, and hypertension. He also has severe obstructive lung disease (forced expiratory volume in 1 second, 39% of the predicted value) with a progressive increase in ...
J. Taylor Hays, Jon O. Ebbert
openalex +4 more sources
BMC Medicine, 2023 Vaping cessation is virtually unexplored. The efficacy and safety of varenicline for vaping cessation has not been studied and rigorous research is required to advance best practice and outcomes for people who use electronic cigarettes (EC) and want to ...
P. Caponnetto +8 more
semanticscholar +1 more source
JAMA Network Open, 2023 This cross-sectional study evaluates the association between the 2021 varenicline tartrate recall and prescribing of varenicline and other medications for nicotine dependence in a large US national patient cohort.
A. E. Lang +5 more
semanticscholar +1 more source
International Journal of Environmental Research and Public Health, 2023 Background: Although varenicline has been used for alcohol dependence (AD) treatment, its efficacy for this condition remains controversial. Aims: This systematic review and meta-analysis of randomized controlled trials (RCTs) assesses the efficacy and ...
Wiraphol Phimarn +4 more
semanticscholar +1 more source
The Antiviral Activity of Varenicline against Dengue Virus Replication during the Post-Entry Stage
Biomedicines, 2023 Dengue virus (DENV) poses a significant global health challenge, with millions of cases each year. Developing effective antiviral drugs against DENV remains a major hurdle. Varenicline is a medication used to aid smoking cessation, with anti-inflammatory
Ching-Lin Lin +10 more
semanticscholar +1 more source
Varenicline Solution Nasal Spray: A Review in Dry Eye Disease
Drugs, 2022 Increasing endogenous tear film production via pharmacological neuroactivation of the nasolacrimal reflex [NLR; also known as the trigeminal parasympathetic pathway (TPP)] is a novel therapeutic approach to treating dry eye disease (DED).
J. Frampton
semanticscholar +1 more source
JAMA Network Open, 2022 This randomized clinical trial compares the effectiveness of varenicline and cytisine with nicotine replacement therapy for reducing alcohol consumption among individuals with HIV who smoke daily and engage in risky drinking.
H. Tindle +14 more
semanticscholar +1 more source