Results 11 to 20 of about 20,079 (290)

The Antiviral Activity of Varenicline against Dengue Virus Replication during the Post-Entry Stage

Biomedicines, 2023
Dengue virus (DENV) poses a significant global health challenge, with millions of cases each year. Developing effective antiviral drugs against DENV remains a major hurdle. Varenicline is a medication used to aid smoking cessation, with anti-inflammatory
Ching-Lin Lin, Yan-Tung Kiu, Ju-Ying Kan, Yu-Jen Chang, Ping-Yi Hung, Chih-Hao Lu, Wen-Ling Lin, Yow-Wen Hsieh, Jung-Yie Kao, Nien-Jen Hu, Cheng-Wen Lin   +10 more
doaj   +2 more sources

Varenicline Prevents LPS-Induced Inflammatory Response via Nicotinic Acetylcholine Receptors in RAW 264.7 Macrophages

Frontiers in Molecular Biosciences, 2021
The cholinergic anti-inflammatory pathway plays an important role in controlling inflammation. This study investigated the effects of varenicline, an α7 nicotinic acetylcholine receptor (α7nAChR) agonist, on inflammatory cytokine levels, cell ...
Elif Baris, Elif Baris, Hande Efe, Mukaddes Gumustekin, Mualla Aylin Arici, Metiner Tosun   +5 more
doaj   +2 more sources

Exposure to varenicline protects against locomotor alteration in a MPTP mouse model of Parkinson's disease

Brazilian Journal of Medical and Biological Research, 2021
The beneficial effects of drugs that act via nicotinic acetylcholine receptors (nAChRs) on Parkinson's disease (PD) symptomatology may explain the negative correlation between cigarette smoking and risk of this neurological condition.
A. Ribeiro-Carvalho, P.H. Leal-Rocha, J. Isnardo-Fernandes, U.C. Araújo, Y. Abreu-Villaça, C.C. Filgueiras, A.C. Manhães   +6 more
doaj   +2 more sources

Neuropsychiatric safety of varenicline in the general and COPD population with and without psychiatric disorders: a retrospective cohort study in a real-world setting

BMJ Open, 2021
Objectives To evaluate the real-world association between varenicline and neuropsychiatric adverse events (NPAEs) in general and chronic obstructive pulmonary disease (COPD) population with and without psychiatric disorders compared with nicotine ...
Yuanyuan Wang, Bob Wilffert, Eelko Hak, H. Marike Boezen, Jens H. Bos, Catharina C.M. Schuiling-Veninga, Job F. M. van Boven   +6 more
doaj   +2 more sources

A randomized trial of varenicline (Chantix) for the treatment of spinocerebellar ataxia type 3. [PDF]

, 2012
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DE MICHELE, GIUSEPPE, FILLA, ALESSANDRO, SACCA', FRANCESCO   +2 more
core   +3 more sources

Evaluation of the cardiovascular effects of varenicline in rats

Drug Design, Development and Therapy, 2015
Engin Burak Selçuk,1 Meltem Sungu,2 Hakan Parlakpinar,3 Necip Ermiş,4 Elif Taslıdere,5 Nigar Vardı,5 Murat Yalçinsoy,6 Mustafa Sagır,3 Alaaddin Polat,7 Mehmet Karatas,8 Burcu Kayhan-Tetik11Department of Family Medicine, 2Inonu University ...
Selçuk EB, Sungu M, Parlakpinar H, Ermiş N, Taslıdere E, Vardı N, Yalçınsoy M, Sagır M, Polat A, Karatas M, Kayhan-Tetik B   +10 more
doaj   +6 more sources

Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial

BMC Medicine, 2023
Vaping cessation is virtually unexplored. The efficacy and safety of varenicline for vaping cessation has not been studied and rigorous research is required to advance best practice and outcomes for people who use electronic cigarettes (EC) and want to ...
P. Caponnetto, D. Campagna, J. Ahluwalia, Christopher Russell, M. Maglia, P. M. Riela, C. Longo, Barbara Busà, R. Polosa   +8 more
semanticscholar   +1 more source

Association of the Chantix Recall With US Prescribing of Varenicline and Other Medications for Nicotine Dependence

JAMA Network Open, 2023
This cross-sectional study evaluates the association between the 2021 varenicline tartrate recall and prescribing of varenicline and other medications for nicotine dependence in a large US national patient cohort.
A. E. Lang, U. Patel, Jonathan Fitzpatrick, Tiffany Lee, Margo McFarland, C. Good   +5 more
semanticscholar   +1 more source

Efficacy of Varenicline in the Treatment of Alcohol Dependence: An Updated Meta-Analysis and Meta-Regression

International Journal of Environmental Research and Public Health, 2023
Background: Although varenicline has been used for alcohol dependence (AD) treatment, its efficacy for this condition remains controversial. Aims: This systematic review and meta-analysis of randomized controlled trials (RCTs) assesses the efficacy and ...
Wiraphol Phimarn, Rotjanawat Sakhancord, Peerasaran Paitoon, Kritsanee Saramunee, Bunleu Sungthong   +4 more
semanticscholar   +1 more source

Efficacy of varenicline versus bupropion for smoking cessation: A systematic review and meta-analysis of randomized controlled trials

Indian Journal of Psychiatry, 2023
According to the Global Burden of Disease (GBD) Study conducted in 2019, smoking tobacco leads to over 8 million deaths each year. Hence, it is crucial to identify optimal smoking cessation therapy. To compare the efficacy of varenicline versus bupropion
Ashish R. Patel, Jigar R. Panchal, Chetna K. Desai   +2 more
doaj   +1 more source