Results 11 to 20 of about 19,681 (252)

Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial

BMC Medicine, 2023
Background Vaping cessation is virtually unexplored. The efficacy and safety of varenicline for vaping cessation has not been studied and rigorous research is required to advance best practice and outcomes for people who use electronic cigarettes (EC ...
Pasquale Caponnetto, Davide Campagna, Jasjit S. Ahluwalia, Christopher Russell, Marilena Maglia, Paolo Marco Riela, Carmelo Fabio Longo, Barbara Busa, Riccardo Polosa   +8 more
doaj   +2 more sources

Two-year efficacy of varenicline tartrate and counselling for inpatient smoking cessation (STOP study): A randomized controlled clinical trial.

PLoS ONE, 2020
IntroductionVarenicline tartrate is superior for smoking cessation to other tobacco cessation therapies by 52 weeks, in the outpatient setting. We aimed to evaluate the long-term (104 week) efficacy following a standard course of inpatient-initiated ...
Kristin V Carson-Chahhoud, Brian J Smith, Matthew J Peters, Malcolm P Brinn, Faisal Ameer, Kuljit Singh, Robert Fitridge, Simon A Koblar, Jim Jannes, Antony J Veale, Sharon Goldsworthy, Khin Hnin, Adrian J Esterman   +12 more
doaj   +2 more sources

Examining the predictive validity of alcohol-seeking following punishment-imposed abstinence in mice. [PDF]

Alcohol Clin Exp Res (Hoboken)
Animal models of alcohol use disorder are critical to understand the neurochemical mechanisms underlying this disorder to inform targeted medication development. However, quite often the validity of commonly used animal models remains untested. Here, we optimized a highly used model of abstinence in mice and demonstrated the predictive validity of the ...
Tran L, Kuznetsova M, Manning EE, Campbell EJ.   +3 more
europepmc   +2 more sources

Association of the Chantix Recall With US Prescribing of Varenicline and Other Medications for Nicotine Dependence.

JAMA Network Open, 2023
This cross-sectional study evaluates the association between the 2021 varenicline tartrate recall and prescribing of varenicline and other medications for nicotine dependence in a large US national patient cohort.
A. E. Lang, U. Patel, Jonathan Fitzpatrick, Tiffany Lee, Margo McFarland, C. Good   +5 more
semanticscholar   +1 more source

Efficacy of Varenicline in the Treatment of Alcohol Dependence: An Updated Meta-Analysis and Meta-Regression

International Journal of Environmental Research and Public Health, 2023
Background: Although varenicline has been used for alcohol dependence (AD) treatment, its efficacy for this condition remains controversial. Aims: This systematic review and meta-analysis of randomized controlled trials (RCTs) assesses the efficacy and ...
Wiraphol Phimarn, Rotjanawat Sakhancord, Peerasaran Paitoon, Kritsanee Saramunee, Bunleu Sungthong   +4 more
semanticscholar   +1 more source

Varenicline Solution Nasal Spray: A Review in Dry Eye Disease

Drugs, 2022
Increasing endogenous tear film production via pharmacological neuroactivation of the nasolacrimal reflex [NLR; also known as the trigeminal parasympathetic pathway (TPP)] is a novel therapeutic approach to treating dry eye disease (DED).
J. Frampton
semanticscholar   +1 more source

Effectiveness of Varenicline and Cytisine for Alcohol Use Reduction Among People With HIV and Substance Use

JAMA Network Open, 2022
This randomized clinical trial compares the effectiveness of varenicline and cytisine with nicotine replacement therapy for reducing alcohol consumption among individuals with HIV who smoke daily and engage in risky drinking.
H. Tindle, M. Freiberg, D. Cheng, N. Gnatienko, E. Blokhina, T. Yaroslavtseva, S. Bendiks, G. Patts, J. Hahn, K. So-Armah, M. Stein, K. Bryant, D. Lioznov, E. Krupitsky, J. Samet   +14 more
semanticscholar   +1 more source

Effect of Cytisine vs Varenicline on Smoking Cessation: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2021
Importance Cytisine is more effective than placebo and nicotine replacement therapy for smoking cessation. However, cytisine has not been tested against the most effective smoking cessation medication, varenicline, which is associated with adverse events
R. Courtney, H. McRobbie, P. Tutka, Natasha Weaver, D. Petrie, C. Mendelsohn, A. Shakeshaft, Saki Talukder, Christel Macdonald, D. Thomas, Benjamin Kwan, Natalie Walker, C. Gartner, R. Mattick, C. Paul, S. G. Ferguson, N. Zwar, R. Richmond, C. Doran, Veronica C. Boland, W. Hall, R. West, M. Farrell   +22 more
semanticscholar   +1 more source

Effect of Combination Treatment With Varenicline and Nicotine Patch on Smoking Cessation Among Smokers Who Drink Heavily

JAMA Network Open, 2022
Key Points Question Is the combination of varenicline tartrate and nicotine patch a more effective treatment than placebo with nicotine patch for smoking cessation in adult cigarette smokers who drink heavily?
Andrea King, Ashley Vena, H. de Wit, J. Grant, Dingcai Cao   +4 more
semanticscholar   +1 more source

E-cigarettes to Augment Stop Smoking In-person Support and Treatment With Varenicline (E-ASSIST): A Pragmatic Randomized Controlled Trial

Nicotine & Tobacco Research, 2022
Aim To examine whether, in adults receiving behavioral support, offering e-cigarettes together with varenicline helps more people stop smoking cigarettes than varenicline alone. Methods A two-group, parallel arm, pragmatic randomized controlled trial was
Harry Tattan-Birch, L. Kock, Jamie Brown, E. Beard, L. Bauld, R. West, L. Shahab   +6 more
semanticscholar   +1 more source