Results 11 to 20 of about 20,263 (262)

Efficacy of varenicline versus bupropion for smoking cessation: A systematic review and meta-analysis of randomized controlled trials

open access: yesIndian Journal of Psychiatry, 2023
According to the Global Burden of Disease (GBD) Study conducted in 2019, smoking tobacco leads to over 8 million deaths each year. Hence, it is crucial to identify optimal smoking cessation therapy. To compare the efficacy of varenicline versus bupropion
Ashish R. Patel   +2 more
doaj   +2 more sources

Varenicline Prevents LPS-Induced Inflammatory Response via Nicotinic Acetylcholine Receptors in RAW 264.7 Macrophages

open access: yesFrontiers in Molecular Biosciences, 2021
The cholinergic anti-inflammatory pathway plays an important role in controlling inflammation. This study investigated the effects of varenicline, an α7 nicotinic acetylcholine receptor (α7nAChR) agonist, on inflammatory cytokine levels, cell ...
Elif Baris   +5 more
doaj   +2 more sources

Exposure to varenicline protects against locomotor alteration in a MPTP mouse model of Parkinson's disease

open access: yesBrazilian Journal of Medical and Biological Research, 2021
The beneficial effects of drugs that act via nicotinic acetylcholine receptors (nAChRs) on Parkinson's disease (PD) symptomatology may explain the negative correlation between cigarette smoking and risk of this neurological condition.
A. Ribeiro-Carvalho   +6 more
doaj   +2 more sources

Varenicline and counseling for vaping cessation: a double-blind, randomized, parallel-group, placebo-controlled trial

open access: yesBMC Medicine, 2023
Background Vaping cessation is virtually unexplored. The efficacy and safety of varenicline for vaping cessation has not been studied and rigorous research is required to advance best practice and outcomes for people who use electronic cigarettes (EC ...
Pasquale Caponnetto   +8 more
doaj   +2 more sources

Effect of Extending the Duration of Prequit Treatment With Varenicline on Smoking Abstinence [PDF]

open access: goldJAMA Network Open, 2022
Key Points Question Does extending the duration of prequit treatment with varenicline improve rates of smoking abstinence? Findings In this randomized clinical trial that included 320 adults, the percentage of bioverified continuous 4-week abstinence ...
Larry W. Hawk   +7 more
openalex   +2 more sources

Pilot safety evaluation of varenicline for the treatment of methamphetamine dependence [PDF]

open access: yesJournal of Experimental Pharmacology, 2009
Todd Zorick1, Rajkumar J Sevak1, Karen Miotto1, Steven Shoptaw2,4, Aimee-Noelle Swanson2, Clayton Clement1, Richard De La Garza II1*, Thomas F Newton1*, Edythe D London1,3,41Departments of Psychiatry and Biobehavioral Sciences, 2Family Medicine ...
Todd Zorick   +3 more
doaj   +2 more sources

Use of low-dose varenicline in hospitalized smokers: A case series low-dose varenicline in hospitalized smokers [PDF]

open access: yesSAGE Open Medical Case Reports
Nicotine replacement therapy is the primary medication used to treat tobacco dependence in hospitalized patients. Recent evidence shows that varenicline is more effective than nicotine replacement, but varenicline side effects limit its use in the ...
Rachael L. Joyner   +3 more
doaj   +2 more sources

Nicotinic acetylcholine receptor-mediated effects of varenicline on LPS-elevated prostaglandin and cyclooxygenase levels in RAW 264.7 macrophages

open access: yesFrontiers in Molecular Biosciences
Introduction: The purpose of this study is to delineate anti-inflammatory and antioxidant potential of varenicline, a cigarette smoking cessation aid, on decreasing lipopolysaccharide (LPS)-elevated proinflammatory cytokines in RAW 264.7 murine ...
Elif Baris   +2 more
doaj   +2 more sources

Varenicline for smoking cessation: efficacy, safety, and treatment recommendations

open access: goldPatient Preference and Adherence, 2010
Jon O Ebbert, Kirk D Wyatt, J Taylor Hays, Eric W Klee, Richard D HurtMayo Clinic College of Medicine, Rochester, MN, USAAbstract: Smoking is the leading preventable cause of morbidity and mortality in the US, and decreasing smoking prevalence is a ...
Jon O Ebbert   +3 more
doaj   +3 more sources

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