Results 51 to 60 of about 20,263 (262)

Implementation of a quality improvement project on smoking cessation reduces smoking in a high risk trauma patient population. [PDF]

, 2016
BackgroundCigarette smoking causes about one of every five deaths in the U.S. each year. In 2013 the prevalence of smoking in our institution's trauma population was 26.7 %, well above the national adult average of 18.1 % according to the CDC website. As
Carrens, Karen, Doben, Andrew, Gross, Ronald, Korntner, Samuel, Nahmias, Jeffry, Poola, Shiva   +5 more
core   +1 more source

Efficacy of Combining Varenicline and Naltrexone for Smoking Cessation and Drinking Reduction: A Randomized Clinical Trial.

American Journal of Psychiatry, 2021
OBJECTIVE Pharmacological treatments that can concomitantly address cigarette smoking and heavy drinking stand to improve health care delivery for these highly prevalent co-occurring conditions.
L. Ray, ReJoyce Green, Craig K. Enders, A. Leventhal, E. Grodin, Gang Li, Aaron C. Lim, E. Hartwell, A. Venegas, Lindsay R Meredith, Steven J. Nieto, S. Shoptaw, Diana Ho, K. Miotto   +13 more
semanticscholar   +1 more source

Evaluation of reproductive and renal toxicity of varenicline in male rats [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Varenicline is a selective partial agonist for the nicotinic acetylcholine receptor a4b2 subtype, which is widely used to treat smoking addiction. However, there is still no data about its potential toxic effects on tissues.
Fatih OĞUZ, Ali Beytur, Elif Taşlıdere, Hakan Parlakpınar, Hilal Oğuz, Alaaddin Polat, İbrahim Topcu, Nigar Vardi, Engin Burak Selcuk   +8 more
doaj   +1 more source

Low Dopamine D2/D3 Receptor Availability is Associated with Steep Discounting of Delayed Rewards in Methamphetamine Dependence. [PDF]

, 2015
BackgroundIndividuals with substance use disorders typically exhibit a predilection toward instant gratification with apparent disregard for the future consequences of their actions.
Ballard, Michael E, Dean, Andy C, Hsu, Eustace, Ishibashi, Kenji, London, Edythe D, Mandelkern, Mark A, Monterosso, John R, Robertson, Chelsea L   +7 more
core   +3 more sources

Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase

Journal of Pharmacological Sciences, 2018
Smoking cessation is the most effective treatment in patients with emphysema and lung inflammation. The aim of the present study was to examine the effect of varenicline, a smoking cessation drug, on emphysema in porcine pancreatic elastase (PPE)-inhaled
Mitsuhisa Koga, Yuki Kanaoka, Tetsushi Tashiro, Nagisa Hashidume, Yasufumi Kataoka, Atsushi Yamauchi   +5 more
doaj   +1 more source

Efficacy and safety of pharmacotherapies for smoking cessation in anxiety disorders: Subgroup analysis of the randomized, active- and placebo-controlled EAGLES trial. [PDF]

, 2020
BackgroundSmoking rates are high in adults with anxiety disorders (ADs), yet little is known about the safety and efficacy of smoking-cessation pharmacotherapies in this group.MethodsPost hoc analyses in 712 smokers with AD (posttraumatic stress disorder
Anthenelli, Robert M, Ayers, Catherine R, Evins, A Eden, Heffner, Jaimee L, Lawrence, David, McRae, Thomas, Russ, Cristina   +6 more
core  

Varenicline for Youth Nicotine Vaping Cessation: A Randomized Clinical Trial.

JAMA
Importance Electronic cigarette use (vaping) among adolescents and young adults is common. Few treatments have been tested in this population. Objective To evaluate the efficacy of varenicline for nicotine vaping cessation in youth who do not smoke ...
Evins AE, Cather C, Reeder HT, Evohr B, Potter K, Pachas GN, Gray KM, Levy S, Rigotti NA, Iroegbulem V, Dufour J, Casottana K, Costello MA, Gilman JM, Schuster RM.   +14 more
europepmc   +2 more sources

Varenicline decreases nicotine but not alcohol self-administration in genetically selected Marchigian Sardinian alcohol-preferring (msP) rats [PDF]

, 2015
Background: Alcohol and nicotine are largely co-abused. Here, we investigated whether concurrent exposure to both addictive drugs influences each other's consumption and whether varenicline attenuates alcohol consumption in the presence of nicotine ...
Ciccocioppo, Roberto, Cippitelli, Andrea, Scuppa, Giulia, Toll, Lawrence, Ubaldi, Massimo   +4 more
core   +1 more source

Efficacy of Electronic Cigarettes vs Varenicline and Nicotine Chewing Gum as an Aid to Stop Smoking

JAMA Internal Medicine
Importance Electronic cigarettes (ECs) are often used by smokers as an aid to stopping smoking, but evidence is limited regarding their efficacy compared with nicotine replacement therapy (NRT), and no evidence is available on how their efficacy compares
Hao-Xiang Lin, Zhao Liu, Peter Hajek, Wan-tong Zhang, Yuan Wu, Bao-chen Zhu, Hai-hua Liu, Qiu Xiang, Yan Zhang, Shu-Bin Li, F. Pesola, Ying-Ying Wang   +11 more
semanticscholar   +1 more source

Efficacy and safety of varenicline and bupropion, in combination and alone, for alcohol use disorder: a randomized, double-blind, placebo-controlled multicentre trialResearch in context

The Lancet Regional Health. Europe
Summary: Background: Alcohol use disorder (AUD) is associated with an enormous burden of disease and cost to society. The dopamine deficiency hypothesis posits that negative reinforcement generated by a low brain dopamine state drives ethanol intake ...
Bo Söderpalm, Helga Lidö, Johan Franck, Anders Håkansson, Daniel Lindqvist, Markus Heilig, Joar Guterstam, Markus Samuelson, Barbro Askerup, Cecilia Wallmark-Nilsson, Andrea de Bejczy   +10 more
doaj   +1 more source