Results 51 to 60 of about 12,608 (240)
Introduction Studies in the general population suggest that varenicline is more effective than nicotine replacement therapy (NRT) for smoking cessation.
Stephanie KY Choi+7 more
doaj +1 more source
Looking Back and Going Forward: Roles of Varenicline and Electronic Cigarettes in Smoking Cessation
Tobacco use is the single largest preventable cause of death in the United States (US). The national goal of reducing the prevalence of adult cigarette smoking to 12% was retained for 20 years due to non-attainment.
Ebenezer O. Oloyede+3 more
semanticscholar +1 more source
Varenicline is a widely used and effective drug for smoking cessation. We have previously reported experimental evidence suggesting that varenicline increases the risk of cardiovascular events.
Mitsuhisa Koga+5 more
doaj
Objective: Varenicline, a selective partial agonist of the α4β2 nicotinic acetylcholine receptor, is a smoking cessation pharmacotherapy that more than doubles the chance of quitting smoking at 6 months compared with placebo. This article reviews salient
S. Tonstad+8 more
semanticscholar +1 more source
Cholinergic System Changes in Dopa‐Unresponsive Freezing of Gait in Parkinson's Disease
Abstract Background Freezing of gait (FoG) is a debilitating mobility disturbance that becomes increasingly resistant to dopaminergic pharmacotherapies with advancing Parkinson's disease (PD). The pathophysiology underlying the response of FoG to dopaminergic treatment is poorly understood.
Kelvin L. Chou+6 more
wiley +1 more source
Light‐Activated Pharmacological Tools for Exploring the Cholinergic System
ABSTRACT Cholinergic transmission plays a critical role in both the central and peripheral nervous systems, affecting processes such as learning, memory, and inflammation. Conventional cholinergic drugs generally suffer from poor selectivity and temporal precision, leading to undesired effects and limited therapeutic efficacy. Photopharmacology aims to
Alessio Colleoni+5 more
wiley +1 more source
Importance Quitting smoking is enhanced by the use of pharmacotherapies, but concerns have been raised regarding the cardiovascular safety of such medications.
Neal L Benowitz+8 more
semanticscholar +1 more source
Varenicline: A new pharmacotherapy for smoking cessation in primary care practice
Background: Cigarette smoking causes significant morbidity and mortality and is a major public health concern worldwide. Primary care doctors are in a unique position that enables them to promote smoking cessation, as smokers are more aware of their ...
N. Robson
doaj +1 more source
Varenicline for smoking cessation: Is it a heartbreaker? [PDF]
See related research article by Singh and colleagues on page [1359][1] and at [www.cmaj.ca/lookup/doi/10.1503/cmaj.110218][2] and related letters on page [1404][3]. In this issue of CMAJ , Singh and colleagues[1][4] present a meta-analysis assessing the risk of serious adverse cardiovascular ...
openaire +3 more sources
Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper+7 more
wiley +1 more source