Results 51 to 60 of about 20,079 (290)

Use of varenicline for smoking cessation treatment in UK primary care: an association rule mining analysis [PDF]

, 2014
BACKGROUND: Varenicline is probably the most effective smoking cessation pharmacotherapy, but is less widely used than nicotine replacement therapy. We therefore set out to identify the characteristics of numerically important groups of patients who ...
Action on Smoking and Health (ASH), AE Evins, British National Formulary (BNF), G Taylor, GD Garrison, IH Witten, John Britton, JS Taggar, K Cahill, KH Thomas, L Szatkowski, M Ragg, National Institute for Health and Care Excellence (NICE), National Institute for Health and Care Excellence (NICE), National Institute for Health and Care Excellence (NICE), R Peters, RM Anthenelli, Royal College of Physicians & Royal College of Psychiatrists, Sarah Lewis, TE Langley, The NHS Information Centre for Health and Social Care, U.S. Food and Drug Administration (FDA), UM Mohanasundaram, Y Huang, Yue Huang   +24 more
core   +3 more sources

Evaluation of reproductive and renal toxicity of varenicline in male rats [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Varenicline is a selective partial agonist for the nicotinic acetylcholine receptor a4b2 subtype, which is widely used to treat smoking addiction. However, there is still no data about its potential toxic effects on tissues.
Fatih OĞUZ, Ali Beytur, Elif Taşlıdere, Hakan Parlakpınar, Hilal Oğuz, Alaaddin Polat, İbrahim Topcu, Nigar Vardi, Engin Burak Selcuk   +8 more
doaj   +1 more source

Low Dopamine D2/D3 Receptor Availability is Associated with Steep Discounting of Delayed Rewards in Methamphetamine Dependence. [PDF]

, 2015
BackgroundIndividuals with substance use disorders typically exhibit a predilection toward instant gratification with apparent disregard for the future consequences of their actions.
Ballard, Michael E, Dean, Andy C, Hsu, Eustace, Ishibashi, Kenji, London, Edythe D, Mandelkern, Mark A, Monterosso, John R, Robertson, Chelsea L   +7 more
core   +3 more sources

Characteristics of first-time varenicline users – A cross-sectional study in Finnish quitters

BMC Public Health, 2017
Background Varenicline is an efficacious medicine for smoking cessation (SC) but little is known about the characteristics of varenicline users. This study examined the characteristics of first-time (naïve) varenicline users in Finland and compared those
Hanna E. Tervonen, Juha H. O. Turunen, Christine L. Baker, Juha Laine, Kari Linden   +4 more
doaj   +1 more source

Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase

Journal of Pharmacological Sciences, 2018
Smoking cessation is the most effective treatment in patients with emphysema and lung inflammation. The aim of the present study was to examine the effect of varenicline, a smoking cessation drug, on emphysema in porcine pancreatic elastase (PPE)-inhaled
Mitsuhisa Koga, Yuki Kanaoka, Tetsushi Tashiro, Nagisa Hashidume, Yasufumi Kataoka, Atsushi Yamauchi   +5 more
doaj   +1 more source

Efficacy and safety of pharmacotherapies for smoking cessation in anxiety disorders: Subgroup analysis of the randomized, active- and placebo-controlled EAGLES trial. [PDF]

, 2020
BackgroundSmoking rates are high in adults with anxiety disorders (ADs), yet little is known about the safety and efficacy of smoking-cessation pharmacotherapies in this group.MethodsPost hoc analyses in 712 smokers with AD (posttraumatic stress disorder
Anthenelli, Robert M, Ayers, Catherine R, Evins, A Eden, Heffner, Jaimee L, Lawrence, David, McRae, Thomas, Russ, Cristina   +6 more
core  

Varenicline: cardiovascular safety [PDF]

Canadian Medical Association Journal, 2011
Serious methodologic issues limit the reliability and relevance of the results of the analysis by Singh and colleagues, in which they reported an “increased risk of serious adverse cardiovascular events” associated with varenicline based on a meta-analysis of 14 studies.[1][1] First ...
openaire   +3 more sources

Varenicline decreases nicotine but not alcohol self-administration in genetically selected Marchigian Sardinian alcohol-preferring (msP) rats [PDF]

, 2015
Background: Alcohol and nicotine are largely co-abused. Here, we investigated whether concurrent exposure to both addictive drugs influences each other's consumption and whether varenicline attenuates alcohol consumption in the presence of nicotine ...
Ciccocioppo, Roberto, Cippitelli, Andrea, Scuppa, Giulia, Toll, Lawrence, Ubaldi, Massimo   +4 more
core   +1 more source

Efficacy of Electronic Cigarettes vs Varenicline and Nicotine Chewing Gum as an Aid to Stop Smoking

JAMA Internal Medicine
Importance Electronic cigarettes (ECs) are often used by smokers as an aid to stopping smoking, but evidence is limited regarding their efficacy compared with nicotine replacement therapy (NRT), and no evidence is available on how their efficacy compares
Hao-Xiang Lin, Zhao Liu, Peter Hajek, Wan-tong Zhang, Yuan Wu, Bao-chen Zhu, Hai-hua Liu, Qiu Xiang, Yan Zhang, Shu-Bin Li, F. Pesola, Ying-Ying Wang   +11 more
semanticscholar   +1 more source

Alcohol use disorder severity moderates clinical response to varenicline.

Alcoholism: Clinical and Experimental Research, 2021
BACKGROUND In a multisite clinical trial, varenicline was effective in reducing drinking in both smoking- and nonsmoking patients with alcohol dependence.
S. Donato, ReJoyce Green, L. Ray
semanticscholar   +1 more source