Results 81 to 90 of about 12,608 (240)

An update of a systematic review and meta‐analyses exploring flavours in intervention studies of e‐cigarettes for smoking cessation

Addiction, Volume 120, Issue 4, Page 770-778, April 2025.
Abstract Aims To determine patterns of e‐cigarette flavour use (sweet, tobacco, menthol/mint) in interventional studies of e‐cigarettes for stopping smoking, and to estimate associations between flavours and smoking/vaping outcomes. Methods Update of secondary data analyses, including meta‐analyses subgrouped by flavour provision and narrative ...
Nicola Lindson, Jonathan Livingstone‐Banks, Ailsa R. Butler, David T. Levy, Phoebe Barnett, Annika Theodoulou, Caitlin Notley, Nancy A. Rigotti, Yixian Chen, Jamie Hartmann‐Boyce   +9 more
wiley   +1 more source

Parasomnias and sleep‐related movement disorders induced by drugs in the adult population: a review about iatrogenic medication effects

Journal of Sleep Research, Volume 34, Issue 2, April 2025.
Summary Parasomnias and sleep‐related movement disorders (SRMD) are major causes of sleep disorders and may be drug induced. The objective of this study was to conduct a systematic review of the literature to examine the association between drug use and the occurrence of parasomnias and SRMD.
Sylvain Dumont, Vanessa Bloch, Agnès Lillo‐Lelouet, Christine Le Beller, Pierre A. Geoffroy, Marc Veyrier   +5 more
wiley   +1 more source

Countering Opioid-induced Respiratory Depression in Male Rats with Nicotinic Acetylcholine Receptor Partial Agonists Varenicline and ABT 594

Anesthesiology, 2020
Background: Opioids can induce significant respiratory depression when administered as analgesics for the treatment of acute, postoperative, and chronic pain.
Jun Ren, Xiuqing Ding, J. Greer
semanticscholar   +1 more source

The data set describing cognitive performance after varenicline administration in a 3-choice serial reaction time task in rats

Data in Brief, 2017
The data shows attentional function, impulsivity, motivation, motor function, and motor activity in rats treated with varenicline, a stop-smoking aid.
Yu Ohmura, Hitomi Sasamori, Iku Tsutsui-Kimura, Takeshi Izumi, Takayuki Yoshida, Mitsuhiro Yoshioka   +5 more
doaj   +1 more source

Varenicline Induced Psychosis [PDF]

Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2012
(2012). Varenicline Induced Psychosis. Klinik Psikofarmakoloji Bulteni-Bulletin of Clinical Psychopharmacology: Vol. 22, No. 1, pp. 110-111.
Bilge Burçak Annagür, Emine Tekinarslan, Ozkan Guler   +2 more
openaire   +2 more sources

2532

Journal of Clinical and Translational Science, 2017
OBJECTIVES/SPECIFIC AIMS: The central goal is to predict the metabolites of varenicline and predictively evaluate their propensities for eliciting an increased binding effect in the brain.
Keeshaloy Thompson, Milton Brown
doaj   +1 more source

Effects of GLP‐1 Receptor Agonists in Alcohol Use Disorder

Basic &Clinical Pharmacology &Toxicology, Volume 136, Issue 3, March 2025.
ABSTRACT In the search for novel treatment strategies for alcohol use disorder (AUD), glucagon‐like peptide‐1 (GLP‐1) receptor agonists (GLP‐1RAs) approved for treating Type 2 diabetes and obesity have caught much attention. GLP‐1 is a naturally occurring peptide produced in the small intestines and the brain, regulating plasma glucose levels and ...
Mette Kruse Klausen, Gitte Moos Knudsen, Tina Vilsbøll, Anders Fink‐Jensen   +3 more
wiley   +1 more source

Synergistic‐like decreases in alcohol intake following combined pharmacotherapy with GLP‐1 and amylin in male rats

British Journal of Pharmacology, Volume 182, Issue 6, Page 1292-1305, March 2025.
Background and Purpose The limited effectiveness of current pharmacological treatments for alcohol use disorder (AUD) highlights the need for novel therapies. These may involve the glucagon‐like peptide‐1 receptor or the amylin receptor, as treatment with agonists targeting either of these receptors lowers alcohol intake.
Cajsa Aranäs, Antonia Caffrey, Christian E. Edvardsson, Jesper Vestlund, Heath D. Schmidt, Elisabet Jerlhag   +5 more
wiley   +1 more source

α7‐Nicotinic Acetylcholine Receptor and Mutated α‐Synuclein Interact in Motor Behaviour and Nigrostriatal Dopamine—Findings With Potential Relevance for a Protective Effect of Cigarette Smoking and Parkinson's Disease

European Journal of Neuroscience, Volume 61, Issue 6, March 2025.
Mice with a mutated human α‐synuclein were crossed with mice lacking the nicotinic α7‐acetylcholine receptor; offsprings were analysed for signs of Parkinson's disease. Mice with mutated α‐synuclein without α7‐acetylcholine receptor had an asymmetry of nigral cell counts and an increased striatal dopamine turnover apart from some motor impairments ...
Christian Pifl, Alexandra Wolf, Mark Elevado, Petra Scholze   +3 more
wiley   +1 more source

Varenicline is a smoking cessation drug that blocks alveolar expansion in mice intratracheally administrated porcine pancreatic elastase

Journal of Pharmacological Sciences, 2018
Smoking cessation is the most effective treatment in patients with emphysema and lung inflammation. The aim of the present study was to examine the effect of varenicline, a smoking cessation drug, on emphysema in porcine pancreatic elastase (PPE)-inhaled
Mitsuhisa Koga, Yuki Kanaoka, Tetsushi Tashiro, Nagisa Hashidume, Yasufumi Kataoka, Atsushi Yamauchi   +5 more
doaj