Results 31 to 40 of about 2,662 (212)
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
In order to design a rotating shaft, it is necessary to investigate the fatigue characteristics under the variable amplitude loading by using a rotating bending fatigue machine.
Toru TAKASE +2 more
doaj +1 more source
The Strain energy density to estimate lifetime of notched components subjected to variable amplitude fatigue loading [PDF]
In the present paper, the approach based on the strain energy density (SED) averaged over a structural volume is reformulated to estimate the lifetime of notched components subjected to variable amplitude (VA) uniaxial fatigue loading.
Zheng Hu, Filippo Berto, Luca Susmel
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Small amplitude variable red giants [PDF]
AbstractSmall amplitude variable red giants were discovered long time ago (Eggen 1969, Henry et al. 2000, Jorison et al. 1997). The revolutionary turning point for the study of this type of variable was due to the work of Wood (2000) and Soszyński et al.
D. R. Xiong, L. Deng
openaire +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
PE-HD fatigue damage accumulation under variable loading based on various damage models
Despite numerous studies on fatigue of polymer materials under variable loading, there is little work on highdensity polyethylene (PE-HD). In this context, an experimental analysis for determining the fatigue strength of PE-100, under constant and ...
M. Bourchak, A. Aid
doaj +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source

