Results 41 to 50 of about 216,626 (261)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Fatigue crack propagation characteristics of rubbery materials under variable amplitude loading

Results in Physics, 2018
Fatigue failure is a critical issue frequently encountered by the rubber components in service. In this work fatigue crack propagation experiments with an edge-notched pure shear specimen under variable amplitude loading, which brings effectiveness in ...
Xiao-Li Wang, Mei-Ying Liao, You Xu, Xiao-Ang Liu   +3 more
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Durability assessment of automotive structures under random variable amplitude loading

Advances in Mechanical Engineering, 2018
Durability assessment is essential for assuring the reliability and safety of automotive structures, which subjects to complex random variable amplitude loadings.
Li-Hui Zhao, Hong-Chang Cai, Tong Wang, Song-Lin Zheng   +3 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

The ping-pang variable amplitude limiter used in the coordinated controller of a hybrid reactive power compensation system

Energy Reports, 2023
The hybrid reactive power compensation system, which connects different reactive power compensation devices to the same bus, will be essential equipment for future power systems.
Yuwei Peng
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

A universal, damage-criterion-independent cycle counting method for multiaxial and variable amplitude fatigue [PDF]

MATEC Web of Conferences, 2019
None of the procedures for cycle-counting defined in the ASTM document with designation E1049-85 (Reapproved 2017) [1] are generally applicable to non-proportional, multi-axial Fatigue.
Janssens K.G. F.
doaj   +1 more source

Diffusion Spectrum Imaging Maps Early Axonal Loss and a Unique Progressive Signal in Neuronal Intranuclear Inclusion Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To delineate specific in vivo white matter pathology in neuronal intranuclear inclusion disease (NIID) using diffusion spectrum imaging (DSI) and define its clinical relevance. Methods DSI was performed on 42 NIID patients and 38 matched controls.
Kaiyan Jiang, Yixiu Pei, Xiaobao Hu, Ying Xiong, Fang Wang, Yanyan Yu, Min Zhu, Dandan Tan, Meihong Zhou, Daojun Hong, Fuqing Zhou   +10 more
wiley   +1 more source

Research on the vibration test load spectrum for bogie frame-mounted tractor motor based on on-track tests

机车电传动, 2023
Ignoring the effects of high-frequency signals and small-amplitude cycles that contribute little to structural fatigue damage, rainflow counting was performed on the vibration load of traction motors to generate a three-dimensional load spectrum.
LI Guoshun, GUO Lirong, CHEN Can, ZHANG Yichao, ZHANG Hongwei   +4 more
doaj