Results 41 to 50 of about 2,816,092 (285)

Artificial molecular machines and motors—Design and control of nanoscale motion

open access: yesFEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

Estimation of fatigue life on heat-treated 0.45%C steel under repeated two-step variable amplitude loading

open access: yesNihon Kikai Gakkai ronbunshu, 2018
In order to design a rotating shaft, it is necessary to investigate the fatigue characteristics under the variable amplitude loading by using a rotating bending fatigue machine.
Toru TAKASE   +2 more
doaj   +1 more source

The Strain energy density to estimate lifetime of notched components subjected to variable amplitude fatigue loading [PDF]

open access: yesFracture and Structural Integrity, 2019
In the present paper, the approach based on the strain energy density (SED) averaged over a structural volume is reformulated to estimate the lifetime of notched components subjected to variable amplitude (VA) uniaxial fatigue loading.
Zheng Hu, Filippo Berto, Luca Susmel
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

ASSESSMENT OF FATIGUE CRACK RATE UNDER CYCLIC LOADING

open access: yesAl-Qadisiyah Journal for Engineering Science, 2014
Fatigue crack growth (FCG) in structures subjected to variable amplitude (VA) loading is a complex phenomenon. Analysing of FCG rate is important for the reliable life of engineering structures.
Muhanad Hamed Mosa
doaj  

PE-HD fatigue damage accumulation under variable loading based on various damage models

open access: yeseXPRESS Polymer Letters, 2017
Despite numerous studies on fatigue of polymer materials under variable loading, there is little work on highdensity polyethylene (PE-HD). In this context, an experimental analysis for determining the fatigue strength of PE-100, under constant and ...
M. Bourchak, A. Aid
doaj   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Home - About - Disclaimer - Privacy