Results 51 to 60 of about 296,333 (284)

Hölder Quasicontinuity in Variable Exponent Sobolev Spaces

open access: yesJournal of Inequalities and Applications, 2007
We show that a function in the variable exponent Sobolev spaces coincides with a Hölder continuous Sobolev function outside a small exceptional set.
Katja Tuhkanen   +2 more
doaj   +1 more source

Nonlocal hyperbolic Stokes system with variable exponent of nonlinearity

open access: yesМатематичні Студії, 2023
In this paper, we study the problem for a nonlinear hyperbolic Stokes system of the second order with an integral term. Sufficient conditions for the uniqueness of the weak solution of this problem are found in a bounded domain. The nonlinear term of the
O. M. Buhrii   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

On approximation properties of functions by means of Fourier and Faber series in weighted Lebesgue spaces with variable exponent [PDF]

open access: yesMathematica Moravica, 2023
In this paper the approximation of functions by linear means of Fourier series in weighted variable exponent Lebesgue spaces was studied. This result was applied to the approximation of the functions by linear means of Faber series in Smirnov classes ...
Jafarov Sadulla Z.
doaj  

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Weighted Hardy-Type Inequalities in Variable Exponent Morrey-Type Spaces

open access: yesJournal of Function Spaces and Applications, 2013
We study the p·→q· boundedness of weighted multidimensional Hardy-type operators Hwα· and ℋwα· of variable order αx, with radial weight wx, from a variable exponent locally generalized Morrey space ℒp·,φ·ℝn,w to another ℒq·,ψ·ℝn,w.
Dag Lukkassen   +3 more
doaj   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Variable Exponent Function Spaces related to a Sublinear Expectation

open access: yesAbstract and Applied Analysis, 2020
In this paper, variable exponent function spaces Lp·, Lbp·, and Lcp· are introduced in the framework of sublinear expectation, and some basic and important properties of these spaces are given.
Bochi Xu
doaj   +1 more source

Continuously-variable survival exponent for random walks with movable partial reflectors

open access: yes, 2001
We study a one-dimensional lattice random walk with an absorbing boundary at the origin and a movable partial reflector. On encountering the reflector, at site x, the walker is reflected (with probability r) to x-1 and the reflector is simultaneously ...
C. Kaiser   +24 more
core   +1 more source

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