Results 51 to 60 of about 27,183 (304)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

On approximation properties of functions by means of Fourier and Faber series in weighted Lebesgue spaces with variable exponent [PDF]

open access: yesMathematica Moravica, 2023
In this paper the approximation of functions by linear means of Fourier series in weighted variable exponent Lebesgue spaces was studied. This result was applied to the approximation of the functions by linear means of Faber series in Smirnov classes ...
Jafarov Sadulla Z.
doaj  

The obstacle problem for degenerate anisotropic elliptic equations with variable exponents and $L^1$-data [PDF]

open access: bronze, 2021
Hocine Ayadi   +45 more
openalex   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The variable exponent De Giorgi class and the variable exponent Hölder continuity

open access: yesCommunications on Pure and Applied Analysis
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Yuan, Ya-Ru, Cui, Zhi-Yuan, Zhao, Dun
openaire   +2 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

The discrete Hardy type variable exponent inequality with decreasing exponent

open access: yesActa et Commentationes Universitatis Tartuensis de Mathematica
The purpose of this note is to obtain the discrete Hardy type variable exponent inequality for the decreasing exponent.
René Castillo   +2 more
openaire   +2 more sources

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