Results 31 to 40 of about 11,358 (231)

Variable-Parameter Impedance Control of Manipulator Based on RBFNN and Gradient Descent

Sensors
During the interaction process of a manipulator executing a grasping task, to ensure no damage to the object, accurate force and position control of the manipulator’s end-effector must be concurrently implemented. To address the computationally intensive
Linshen Li, Fan Wang, Huilin Tang, Yanbing Liang   +3 more
doaj   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Variable-Damping Impedance Control for Contact Tasks: A Reinforcement Learning Method Integrating HER and Importance Sampling

Sensors
Force control is crucial for robotic contact-rich tasks such as assembly, grinding, and polishing, directly affecting task accuracy, interaction stability, and safety. Yet in unstructured environments, environmental uncertainty, contact oscillations, and
Xiaoqiang Guo, Hongchang Ding, Xin Ning, Han Hou, Jinhua Cai   +4 more
doaj   +1 more source

Variable Impedance Control Combining Reinforcement Learning and Gaussian Process Regression

2024 IEEE-RAS 23rd International Conference on Humanoid Robots (Humanoids)
Variable Impedance Control (VIC) approaches offer effective means for enabling robots to perform physical interaction tasks safely and proficiently, by including timevarying gains within an impedance control loop. However, determining the optimal gain profiles can be tedious and timeconsuming.
Paolino De Risi, Fabio Amadio, Gianluca Garofalo, Fanny Ficuciello, Pietro Falco   +4 more
openaire   +4 more sources

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Damping profile learning for human-robot collaboration using Bayesian optimization with a task success rate model

Mechanical Engineering Journal
In the realm of human-robot collaboration, impedance and admittance control are widely utilized techniques to regulate the interaction dynamics between humans and robots.
Liem Duc TRAN, Tasuku YAMAWAKI, Masahito YASHIMA   +2 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Variable Impedance Control in End-Effector Space: An Action Space for Reinforcement Learning in Contact-Rich Tasks [PDF]

2019 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS), 2019
IROS19
Roberto Martín-Martín, Michelle A. Lee, Rachel Gardner, Silvio Savarese, Jeannette Bohg, Animesh Garg   +5 more
openaire   +2 more sources