Results 121 to 130 of about 1,393,828 (262)

Elastic Correlation Adjusted Regression (ECAR) scores for high dimensional variable importance measuring. [PDF]

Sci Rep, 2021
Zhou Y, Fa B, Wei T, Sun J, Yu Z, Zhang Y.   +5 more
europepmc   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Nonparametric variable importance assessment using machine learning techniques. [PDF]

Biometrics, 2021
Williamson BD, Gilbert PB, Carone M, Simon N.   +3 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Corrigendum: Identification of Variable Importance for Predictions of Mortality From COVID-19 Using AI Models for Ontario, Canada. [PDF]

Front Public Health, 2021
Snider B, McBean EA, Yawney J, Gadsden SA, Patel B.   +4 more
europepmc   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Identification of Variable Importance for Predictions of Mortality From COVID-19 Using AI Models for Ontario, Canada. [PDF]

Front Public Health, 2021
Snider B, McBean EA, Yawney J, Gadsden SA, Patel B.   +4 more
europepmc   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Portfolio Construction Under Behavioral Distortions and Narrow Framing: A Machine Learning Approach

Mathematics
This paper develops a portfolio construction methodology integrating behavioral finance principles with machine learning to model how cognitive biases systematically alter asset allocation decisions.
Georgios Tsomidis
doaj   +1 more source

Discussion on "Nonparametric variable importance assessment using machine learning techniques" by Brian D. Williamson, Peter B. Gilbert, Marco Carone, and Noah Simon. [PDF]

Biometrics, 2021
Lu M, Ishwaran H.
europepmc   +1 more source