Results 91 to 100 of about 152,408 (254)

Connecting the distribution and diversification of marine plants

Oikos, EarlyView.
Integration of the evolutionary history with distribution of extant species is necessary to explain present‐day diversity, particularly for ‘foundation' species, such as seagrasses, which create habitats of socioecological relevance. Here, we resolved if varying evolutionary history of seagrass families has imprinted the distribution ranges of extant ...
Fernando Tuya, Javier Martínez‐ Pérez, Álvaro Fueyo, Néstor E. Bosch   +3 more
wiley   +1 more source

Waves of range dynamics and gene flow characterize the biogeographic history of Litsea elongata, a dominant tree in East Asian evergreen broadleaved forests

PLANTS, PEOPLE, PLANET, EarlyView.
Evergreen broadleaved forests (EBLFs) represent an iconic vegetation type in subtropical montane East Asia, but they are experiencing intensifying anthropogenic pressure and increasing habitat fragmentation. Here, using a dominant and widespread tree species characteristic of East Asian EBLFs, we examine its phylogeographic history and evaluate what it
Sheng‐Yuan Qin, Richard H. Ree, Zheng‐Yu Zuo, Chih‐Chieh Yu, Shuang‐Xiu Xu, Jun Rong, Peng‐Fei Ma, De‐Zhu Li   +7 more
wiley   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

Accelerating virtual patient generation with a Bayesian optimization and machine learning surrogate model

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 486-494, March 2025.
Abstract The pharmaceutical industry has increasingly adopted model‐informed drug discovery and development (MID3) to enhance productivity in drug discovery and development. Quantitative systems pharmacology (QSP), which integrates drug action mechanisms and disease complexities to predict clinical endpoints and biomarkers is central to MID3.
Hiroaki Iwata, Ryuta Saito
wiley   +1 more source

Adaptive CUSUM Chart for Simultaneous Monitoring of Mean and Variance

Quality and Reliability Engineering International, EarlyView.
ABSTRACT Simultaneously monitoring changes in both the mean and variance is a fundamental problem in statistical process control, and numerous methods have been developed to address it. However, many existing approaches face notable limitations: Some rely on tuning parameters that can significantly affect performance; others are biased toward detecting
Gokul Parakulum, Jun Li
wiley   +1 more source

Why Autonomous Vehicles Are Not Ready Yet: A Multi‐Disciplinary Review of Problems, Attempted Solutions, and Future Directions

Journal of Field Robotics, EarlyView.
ABSTRACT Personal autonomous vehicles can sense their surrounding environment, plan their route, and drive with little or no involvement of human drivers. Despite the latest technological advancements and the hopeful announcements made by leading entrepreneurs, to date no personal vehicle is approved for road circulation in a “fully” or “semi ...
Xingshuai Dong, Massimiliano Cappuccio, Fady Alnajjar, Luqman Ali, Hamad Al Jassmi, Essam Debie, Milad Ghasrikhouzani, Alessandro Lanteri, Tate McGregor, Oleksandra Molloy, Alice Plebe, Michael Regan, Eduardo Sandoval, Dongmo Zhang   +13 more
wiley   +1 more source

Hybrid closed-loop systems for managing blood glucose levels in type 1 diabetes: a systematic review and economic modelling

Health Technology Assessment
Background Hybrid closed-loop systems are a new class of technology to manage type 1 diabetes mellitus. The system includes a combination of real-time continuous glucose monitoring from a continuous glucose monitoring device and a control algorithm to ...
Asra Asgharzadeh, Mubarak Patel, Martin Connock, Sara Damery, Iman Ghosh, Mary Jordan, Karoline Freeman, Anna Brown, Rachel Court, Sharin Baldwin, Fatai Ogunlayi, Chris Stinton, Ewen Cummins, Lena Al-Khudairy   +13 more
doaj   +1 more source

Incorporating environmental DNA metabarcoding for improved benthic biodiversity and habitat mapping

Remote Sensing in Ecology and Conservation, EarlyView.
Seafloor imagery is commonly used to collect information about the distribution of benthic organisms in order to generate habitat and biodiversity maps. Recent advances in genomics (e.g., environmental DNA; eDNA) show potential to complement video surveys for habitat mapping, but there have been few examples testing this.
Rylan J. Command, Shreya Nemani, Benjamin Misiuk, Mehrdad Hajibabaei, Nicole Fahner, Emily Porter, Greg Singer, Beverly McClenaghan, Katleen Robert   +8 more
wiley   +1 more source

Temporal Dynamics of Tourism Sustainability: Economic and Environmental Evidence From Greece

Sustainable Development, EarlyView.
ABSTRACT Tourism is a resource‐intensive sector that generates substantial economic benefits while exerting long‐term pressure on energy systems and the environment. This study examines the sustainability of tourism in Greece by analyzing how tourism growth affects economic performance, energy consumption, and carbon emissions across different time ...
Stylianou Tasos
wiley   +1 more source