Dynamic effects of variable G or variable mass
M. P. Savedoff, S. Vila
openaire +1 more source
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Prediction of on-water performance in outrigger canoeing using laboratory tests: the influence of sex and anthropometric characteristics. [PDF]
Estácio Costa F +3 more
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
Theoretical analysis for heat and mass transfer in bioconvective ternary hybrid nanofluid flow with entropy optimization. [PDF]
Haq F +4 more
europepmc +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
Influence of Chronological Age, Anthropometric Characteristics and Biological Maturity on Eccentric Knee Flexion Strength During the Nordic Hamstring Exercise in Female International Youth Soccer Players. [PDF]
Hickey JT +4 more
europepmc +1 more source
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
RESEARCH ON ACTIVE CONTROL OF VARIABLE MASS SEAT SUSPENSION USING PD CONTROL
Aiming at the system non-linearity caused by the change of load mass of seat suspension and the effective control of seat vibration, an active control system of variable mass seat suspension based on the proportional-derivative (PD) control was proposed.
AN CunSheng +3 more
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