Results 201 to 210 of about 6,770,883 (257)

Predicting concurrent endometrial carcinoma in women with endometrial intraepithelial neoplasia without preoperative suspicion of malignancy. [PDF]

Gynecol Oncol Rep
Zeevi G, Yeoshoua E, Dahan C, Bercovich O, Raban O, Jakobson-Setton A, Sabah G, Matot R, Borovich A, Eitan R.   +9 more
europepmc   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Body Composition and Physical Fitness in Five-a-Side Soccer for the Blind Players: A Penalized Regression Approach. [PDF]

Sports (Basel)
Becerra-Patiño BA, Paucar-Uribe JD, Peñuela-Argüello MA, Zapatá-Piratova CD, Monterrosa-Quintero A, Yáñez-Sepúlveda R, López-Gil JF, Pino-Ortega J.   +7 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

A 35-Year-Old Woman With Multiple Sclerosis and a New Atypical Thalamic Lesion: A Case Report From the National Multiple Sclerosis Society Case Conference Proceedings. [PDF]

Neurol Neuroimmunol Neuroinflamm
Michaelson NM, Arrillaga-Romany IC, Jordan JT, Martinez-Lage M, Riley C, Zamvil SS, Goldman MD, Klawiter EC.   +7 more
europepmc   +1 more source

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

Influence of Temperature and Osmolytes on Conformational Dynamics of Alpha Synuclein. [PDF]

J Phys Chem B
Hampton J, Lynch C, Rider RL, Lantz C, Xi Z, Russell DH.   +5 more
europepmc   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Pain, Low Muscle Mass, and Exercise Participation After Myocardial Infarction: Determinants of Initial Exercise Testing at a Tertiary Center Serving a Rural Region. [PDF]

J Clin Med
Lee JJ, Joo MC, Lee ES, Kim YB, Kim JH.
europepmc   +1 more source

Characterization of the key membrane protein cytochrome Cyc2 from Ghiorsea bivora

FEBS Open Bio, EarlyView.
This study reports the first detailed biochemical analysis of Cyc2TAG1_1, a cytochrome protein involved in microbial iron oxidation. We produced and purified this enzyme in E. coli, then measured its iron‐oxidizing efficiency, and characterized its electrical and structural properties.
Josiane Azizi, Alain Dolla, Frauke Baymann, Celine Rommevaux, Latifa Elantak, Helene Gaussier, Matthieu Nouailler   +6 more
wiley   +1 more source