Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
Measuring the spatial lag effect of Tobler's First Law of Geography in Earth system predictive learning. [PDF]
Zhou P, Liu Y, Chen K, Deng M, Li Q.
europepmc +1 more source
This review establishes structure‐property‐mechanism relationships across six modification strategies for V‐based oxide water‐splitting electrocatalysts: lattice engineering, heteroatom doping, interface engineering, carbon‐based hybridization, morphology engineering, and surface reconstruction and pre‐catalyst design, where dissolution is reframed as ...
Youness El Issmaeli +4 more
wiley +1 more source
Automated model selection in population pharmacokinetics using metaheuristic algorithms
Huang Z +3 more
europepmc +1 more source
The association between social capital and diabetes control: a systematic review and meta-analysis. [PDF]
Chen Y, Chen Z, Gu Z, Hu J.
europepmc +1 more source
An event-driven hybrid rescheduling approach for integrated process planning and scheduling considering stochastic rework. [PDF]
Shi S +6 more
europepmc +1 more source
Improved Egret Swarm Optimization Algorithm Based on Variable-Factor Weighted Learning and Adjacent Generation Dimension Crossover Strategy. [PDF]
Wang S, Zheng Y, Wang P, Cheng Z.
europepmc +1 more source
Epistasis plays a limited role in driving entrenchment during neutral protein evolution. [PDF]
Schmelkin L +6 more
europepmc +1 more source
Optimization of Farmland Cultivated Land Path Based on Hybrid Adaptive Neighborhood Search Algorithm. [PDF]
Lv H, Yao Z, Zhang T.
europepmc +1 more source
An improved adaptive large neighborhood search algorithm for the flexible two-tier vehicle routing problem with drone stations. [PDF]
Li Q, Yan W, Gonsalves T.
europepmc +1 more source

