Results 171 to 180 of about 5,591,095 (382)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

The Puzzle of V407 Cygni

open access: yesActa Polytechnica, 2011
We discuss the nature and recent observations (optical and gamma-rays) of symbiotics binary/Mira variable V407 Cygni. In addition we discuss another object of similar category, namely the variable star FY Aql with possible association with an eruptive ...
R. Hudec
doaj  

An Episode of Occultation Events in Gaia21bcv

open access: yesThe Astronomical Journal
A previously unremarkable star near the Canis Major OB1/R1 association underwent an episode of multiple deep brightness minima. Light curves based on archival Gaia, Zwicky Transient Facility (ZTF), and NEOWISE data and additional observations from the ...
Klaus W. Hodapp   +6 more
doaj   +1 more source

Photometric Flickering of the CH CYG IN 2018

open access: yesEast European Journal of Physics
Photometric observations of the CH Cyg symbiotic star were conducted using the Zeiss 600 telescope at the ShAO (Shamakhy Astrophysical Observatory) between 06.07.2018 and 16.09.2018 over the course of 17 nights with the V-filter. The light curve for this
Kh.M. Mikailov, R.T. Mammadov
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

Home - About - Disclaimer - Privacy