Results 91 to 100 of about 349,394 (283)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Variable Stars in M31 Stellar Clusters from the Panchromatic Hubble Andromeda Treasury

The Astrophysical Journal
Variable stars in stellar clusters can offer key constraints on stellar evolution and pulsation models, utilizing estimates of host cluster properties to constrain stellar physical parameters.
Richard Smith, Avi Patel, Monika D. Soraisam, Puragra Guhathakurta, Pranav Tadepalli, Sally Zhu, Joseph Liu, Léo Girardi, L. Clifton Johnson, Sagnick Mukherjee, Knut A. G. Olsen, Benjamin F. Williams   +11 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

ASASSN-16dv: Superhumps in a Long-period X-Ray-luminous Dwarf Nova

The Astronomical Journal
Combining a long-term light curve, four-color rapid photometry, and spectroscopic and X-ray observations with a 27-day time base TESS light curve, we present the first dedicated study of ASASSN-16dv, detected as a transient in the All-Sky Automated ...
Albert Bruch, Raimundo Lopes de Oliveira, Amanda Silva de Araujo, Romualdo Eleutério, Angela Cristina Krabbe, Koji Mukai   +5 more
doaj   +1 more source

”ASYMPTOTIC PARABOLA” FITS FOR SMOOTHING GENERALLY ASYMMETRIC LIGHT CURVES

Odessa Astronomical Publications, 2016
A computer program is introduced, which allows to determine statistically optimal approximation using the "Asymptotic Parabola" fit, or, in other words, the spline consisting of polynomials of order 1,2,1, or two lines ("asymptotes") connected with a ...
K. D. Andrych, I. L. Andronov, L. L. Chinarova, V. I. Marsakova   +3 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

TESS Light Curves of Cataclysmic Variables. V. Improved or Corrected Orbital Periods of 53 Systems

The Astronomical Journal
The long and continuous high-time-resolution coverage of many stars by the Kepler and TESS space missions permit to explore periodic phenomena with a much higher precision than is possible with terrestrial observations.
Albert Bruch
doaj   +1 more source

ABOUT THREE CATACLYSMIC VARIABLE STARS

Odessa Astronomical Publications, 2017
In order to detect the new outbursts of the three cataclysmic variable TV Crv, NSV 1775, NSV 895, their positions was scanned on the plates of the Odessa collection of the sky service obtained for the period 1958 - 1988. The new outbursts were detected
A. V. Klabukova
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source