Results 91 to 100 of about 2,526,596 (235)

TESS Light Curves of Cataclysmic Variables. V. Improved or Corrected Orbital Periods of 53 Systems

open access: yesThe Astronomical Journal
The long and continuous high-time-resolution coverage of many stars by the Kepler and TESS space missions permit to explore periodic phenomena with a much higher precision than is possible with terrestrial observations.
Albert Bruch
doaj   +1 more source

An evaluation of ISIS

open access: yes, 2014
ISIS is a program that specializes in detecting variable stars within clusters, both open and globular. ISIS has historically been used in surveys searching for variable stars.
Bodee, Bradley Robert
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Period–Luminosity Relations for Double-mode δ Sct Stars

open access: yesThe Astrophysical Journal
Previous studies of the period–luminosity relations (PLRs) of Delta Scuti ( δ Sct) stars have focused on those with a single pulsation mode. However, for δ Sct stars with many different pulsation modes, classifying a single mode is difficult.
Qi Jia   +5 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Stellar Variability toward the Galactic Open Cluster NGC 7209

open access: yesThe Astrophysical Journal
We present the analysis of stellar variability in an open cluster NGC 7209 using optical V -band CCD photometric observations. Out of 4499 stars in our study, we detected 284 candidate variables, including one identified previously.
Dorothy M. Mwanzia   +10 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

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