Results 141 to 150 of about 4,932,223 (296)

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

The Optical Gravitational Lensing Experiment. The OGLE-III Catalog of Variable Stars. IX. RR Lyrae Stars in the Small Magellanic Cloud [PDF]

, 2010
I. Soszyński, A. Udalski, M. K. Szymański, M. Kubiak, G. Pietrzyński, Ł. Wyrzykowski, K. Ulaczyk, R. Poleski   +7 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source

Envelope tomography of long-period variable stars: I. The Schwarzschild mechanism and the Balmer emission lines [PDF]

, 2000
R. Álvarez, A. Jorissen, B. Plez, Denis Gillet, Andrej Fokin   +4 more
openalex   +1 more source

A survey for variable young stars with small telescopes: V - Analysis of TXOri, V505Ori, and V510Ori, the HST ULLYSES targets in the $\sigma$Ori cluster [PDF]

, 2021
D. Froebrich, J. Eislöffel, B. Stecklum, Carys Herbert, Franz-Josef Hambsch   +4 more
openalex   +1 more source

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

Molecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla, Simone Venz, Ruslan Al‐Ali, Martin Wendlandt, Mandy Radefeldt, Elke Krüger   +5 more
wiley   +1 more source

The Isaac Newton Telescope Monitoring Survey of Local Group Dwarf Galaxies. VII. Long-Period Variable Stars in the Nearest Starburst Dwarf Galaxy, IC 10 [PDF]

Mahtab Gholami, Atefeh Javadi, Hamidreza Mahani, Jacco van Loon, Habib G. Khosroshahi, Elham Saremi, Iain McDonald, Samaneh Eftekhari, Yi Ren, Hamed Altafi   +9 more
openalex   +1 more source

Variable stars observed with the AST3-1 telescope from dome A of antarctica [PDF]

, 2015
Gang Li, Jian-Ning Fu, Xuanming Liu
openalex   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

Molecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu, Katherine Eason, Suet‐Feung Chin, Paul A. W. Edwards, Raquel Manzano Garcia, Richard Moulange, Jia Wern Pan, Soo Hwang Teo, Sach Mukherjee, Maurizio Callari, Carlos Caldas, Stephen‐John Sammut, Oscar M. Rueda   +12 more
wiley   +1 more source

A Systematic Search for New δ Scuti and γ Doradus Stars Using TESS Data

Universe
Focusing on the discovery of new δ Scuti and γ Doradus stars, we analyzed the Transiting Exoplanet Survey Satellite (TESS) light curves for 193,940 A-F stars selected from four legacy catalogs—the Henry Draper Catalogue (HD), the Smithsonian ...
Ai-Ying Zhou
doaj   +1 more source