Results 91 to 100 of about 2,995,258 (284)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
On Convex Variable Step-Size Algorithm Implementation
, 2005 Publication in the conference proceedings of EUSIPCO, Antalya, Turkey ...
Rusu, Corneliu, Cowan, C.F.N.
openaire +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Variable step-size evolving participatory learning with kernel recursive least squares applied to gas prices forecasting in Brazil. [PDF]
Evol Syst (Berl), 2022 Queiroz ERC +3 more
europepmc +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
PERFORMANCE IMPROVEMENTSOF ADAPTIVE FIR EQUALIZER USINGMODIEFED VERSION OF VSSLMS ALGORITHM
Journal of Engineering, 2007 In this paper possible improvements in the performance of adaptive Linear Equalizer (LE) and Decision Feed Back Equalizer (DFE) are reported. A modified Least Mean Square (LMS) algorithm incorporating a recursively adjusted adaptation step size based on
Thamer M.J. Al-anbaky
doaj +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Low-complexity variable step-size sign algorithm based on Weibull distribution function
Dianxin kexue, 2018 The performance of the traditional second-order statistics based channel estimation methods degrade seriously in the presence of impulsive noises.In order to deal with this problem,a Weibull distribution function based variable step-size sign algorithm ...
Rui ZHANG +3 more
doaj +2 more sources