Results 111 to 120 of about 8,444,075 (296)

Variable step-size LMS adaptive filters for CDMA multiuser detection

open access: yes, 2004
Due to its simplicity the adaptive Least Mean Square (LMS) algorithm is widely used in Code-Division Multiple access (CDMA) detectors. However its convergence speed is highly dependent on the eigen value spread of the input covariance matrix.
Karen Egiazarian   +2 more
core   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Improved Control of PV System using Variable Step Size

open access: yes
In the present context, where industrial, economic, and ecological development are the priorities, photovoltaic energy stands as a favorable option when compared to the use of fossil fuels, which are known to be harmful to the environment.
Mohamed Lemine Bakayoko Yaye yébé   +1 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Expanded Trigonometrically Matched Block Variable-Step-Size Technics for Computing Oscillating Vibrations [PDF]

open access: yes, 2019
The expanded trigonometrically matched block variable-step-size technics for computing oscillatory vibrations are considered. The combination of both is of import for determining a suited step-size and yielding better error estimates.
Oghonyon, J. G.   +2 more
core  

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

A variable step-size adaptive algorithm for direct frequency estimation

open access: yes, 2018
A frequency estimator based on the linear prediction property of sinusoidal signals has recently been proposed for the direct estimation of real tone frequency in white noise.
Lee, CW, Kim, SW, Ban, SJ, Cho, H
core   +1 more source

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