Results 121 to 130 of about 771,544 (300)

A collocation formulation of multistep methods for variable step-size extensions

, 2002
Multistep methods are classically constructed by specially designed difference operators on an equidistant time grid. To make them practically useful, they have to be implemented by varying the step-size according to some error-control algorithm.
Führer, Claus, Arévalo, Carmen, Selva, M   +2 more
core   +1 more source

Research on the performance degradation assessment method of a mine hoist braking system based on variable step-size fruit fly optimization algorithm-complex Gaussian wavelet support vector data description. [PDF]

Sci Prog, 2020
Li J, Meng G, Luo J, Wang A, Ding J, Zhang W.   +5 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

A band-dependent variable step-size sign subband adaptive filter

, 2018
This letter proposes a band-dependent variable step-size sign subband adaptive filter using the concept of mean-square deviation (MSD) minimization. Since it is difficult to obtain the value of the MSD accurately, the proposed step size is derived by ...
Park, P, Yoo, J, Shin, J
core   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

The Wavelet Transform-Domain LMS Adaptive Filter Algorithm with Variable Step-Size

Iranian Journal of Electrical and Electronic Engineering, 2017
The wavelet transform-domain least-mean square (WTDLMS) algorithm uses the self-orthogonalizing technique to improve the convergence performance of LMS.
M. Shams Esfand Abadi, H. Mesgarani, S. M. Khademiyan   +2 more
doaj  

GWO and WOA variable step MPPT algorithms-based PV system output power optimization

Scientific Reports
The nonlinear characteristics and low efficiency of photovoltaic (PV) systems remain critical challenges that necessitate advanced solutions. This study proposes two innovative Maximum Power Point Tracking (MPPT) algorithms based on the Whale ...
Abderrahim Zemmit, Abdelouadoud Loukriz, Khaled Belhouchet, Yahya Z. Alharthi, Muhannad Alshareef, Prabhu Paramasivam, Sherif S. M. Ghoneim   +6 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source