Results 131 to 140 of about 599,512 (246)

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Nurturing Care Systems Underlying Early Childhood Food Insecurity in Brazil: A Causal Loop Diagram Approach. [PDF]

Matern Child Nutr
Buccini G, Stave KA, Marçal K, Venancio SI, Gubert MB, Pérez-Escamilla R.   +5 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Modeling nonlinear variable-order fractional chaotic systems using the Caputo-Fabrizio operator and radial basis function neural networks. [PDF]

Sci Rep
Sawar S, Ayaz M, Aldhabani MS, Abd El-Rahman M, Hussain S, Jebran S.   +5 more
europepmc   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Hacking continuous-variable quantum key distribution using the photorefractive effect on proton-exchanged/annealed-proton-exchanged waveguide. [PDF]

Sci Rep
Mao N, Zhang H, Zuo Z, Wang Y, Mao Y, Guo Y.   +5 more
europepmc   +1 more source

An Adaptation Mechanism of Model Reference Adaptive System Based on Variable Structure Control for Online Parameter Estimation of IPMSM

Ertuğrul Ateş, Burak Tekgün, MURAT BARUT   +2 more
openalex   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

A study on carbon emission prediction of multi-energy complementary power system based on multiple linear regression model. [PDF]

Carbon Balance Manag
Sha J, Kang W, Ma R, Zhu D, Liu J.
europepmc   +1 more source

Proposal for A Context-oriented Modelica Contributing to Variable Structure Systems

Zizhe Wang, Manuel Krombholz, Uwe Aßmann, John Tinnerholm, Christian Gutsche, Volodymyr Prokopets, Sebastian Götz   +6 more
openalex   +2 more sources