Results 31 to 40 of about 1,773 (115)

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Collagen Membrane Fixation Technique Affects Its Space Maintenance Capacity After Flap Closure: An Ex Vivo Analysis

Clinical Oral Implants Research, EarlyView.
ABSTRACT Aims To quantify immediate graft displacement following tension‐free flap closure in non‐contained alveolar ridge defects regenerated using three membrane fixation strategies in an ex vivo human model. Methods Eighteen sites from six fresh cadaveric heads with non‐contained defects underwent horizontal guided bone regeneration using ...
Muhammad H. A. Saleh, Javier Calatrava, Nataly Zambrana, Lucrezia Parma‐Benfenati, Hamoun Sabri, Istvan Urban, Hom‐Lay Wang   +6 more
wiley   +1 more source

The sorting nexin Snx21 promotes flotillin‐mediated endocytosis

The FEBS Journal, EarlyView.
In this study, we describe a novel function of the previously uncharacterized Snx21 protein as a specific positive regulator of flotillin‐mediated endocytic trafficking. Snx21 is recruited to endosomal membranes via binding to PI(3)P, and it colocalizes with flotillins on the surface of late endosomes.
Tamás Maruzs, Enikő Lakatos, Dalma Feil‐Börcsök, Gábor Juhász, Regina Mező, Asha Kiran Maddali, András Blastyák, Aladár Pettkó‐Szandtner, Hajnalka Laczkó‐Dobos, Gábor Juhász   +9 more
wiley   +1 more source

Delphi consensus: First‐line use of biologics and small molecules in hidradenitis suppurativa

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This Delphi Consensus study identified upgrade criteria for the use of biologics and small molecules as first‐line therapy in hidradenitis suppurativa (HS). European HS experts evaluated 16 clinical scenarios, voting on eligibility for therapy escalation.
Georgios Nikolakis, Erkan Alpsoy, Florian Anzengruber, Matthias Augustin, Falk G. Bechara, Pierre‐André Becherel, Farida Benhadou, Vincenzo Bettoli, Joana Cabete, Raffaele Dante Caposiena Caro, Antonella Di Cesare, Giovanni Damiani, Valentina Dini, Evangelos J. Giamarellos‐Bourboulis, Krisztián Gáspár, Katalin Glasenhardt, Philippe Guillem, Ariela Hafner, Barbara Horvath, John R. Ingram, Vaiva Jarienè, Gregor B. E. Jemec, Alexander Katoulis, Natalia Kirsten, Georgios Kokolakis, Piotr K. Krajewski, Aikaterini I. Liakou, Flavia Manzo Margiotta, Angelo V. Marzano, Antonio Martorell, Lukasz Matusiak, Dillon Mintoff, Alejandro Molina Leyva, Andreas Pinter, Anna Pirogova, Maurizio Podda, Francesca Prignano, Jorge Romani, Marco Romanelli, Elia Rosi, Samed Sahin, Ditte M. L. Saunte, Sylke Schneider‐Burrus, Mariano Suppa, Jacek Szepietowski, Andrea Szegedi, Simon Francis Thomsen, Thrasyvoulos Tzellos, Anastasia Trigoni, Hessel H. Van Der Zee, Kelsey Van Straalen, Skaidra Valiukevičiene, Eva Vilarrasa, Esther von Stebut, Christos C. Zouboulis   +54 more
wiley   +1 more source

Peri‐Implant Soft‐Tissue Phenotype Modification for Refractory Peri‐Implant Mucositis: A 12‐Month Prospective Clinical Study With Ultrasonographic Analysis

Journal of Periodontal Research, EarlyView.
Surgical treatment of refractory peri‐implant mucositis with a free gingival graft (FGG) was effective in disease resolution, achieving reductions in probing pocket depth (PPD) and inflammation. Significant gains in mucosal thickness (MT) and keratinized mucosa width (KMW), as well as partial recession coverage and re‐establishment of attached mucosa ...
Shayan Barootchi, Lorenzo Tavelli, Hamoun Sabri, Hom‐Lay Wang, Erfan Barootchi, Mario Romandini, Istvan A. Urban, Zoltan Barath   +7 more
wiley   +1 more source

Factors influencing international beer trade

, 2020
Beer has been presenting in human life for a long time. The oldest written proof of beer production, the “Monument Bleu”, comes from Mesopotamia, the 3rd millennium BC and by this time brewing was regulated by law (Ulischberger, 1982).
Jámbor, Attila, Jantyik, Lili, Török, Áron   +2 more
core   +1 more source

School segregation, school choice and educational policies in 100 Hungarian towns [PDF]

, 2013
The distribution of Romani and non-Romani students across schools has become considerably more unequal in Hungary since the 1980s. This paper analyzes the effect of school choice and local educational policies on that inequality, known as school ...
Kertesi, Gábor, Kézdi, Gábor
core  

On the importance of shelter availability for reptiles provided by burrow‐digging ecosystem engineers: A systematic review and a case study

Journal of Zoology, EarlyView.
In this article, we show that ground burrows influenced reptile populations inconsistently across both the 5‐year field study in the Kiskunság and the broader systematic review, which together revealed positive, negative, and neutral effects across species and habitat types.
B. Bancsik, A. Móré, B. Wenner, G. Rák, M. Budai, G. Kovács, B. Nagy, Z. Ladnyik, M. Szabolcs, E. Mizsei   +9 more
wiley   +1 more source

Types of competitiveness of Hungarian regions: agglomeration economies and endogenous regional development [PDF]

Nowadays, more and more scholars of regional science are interested in the role of agglomeration economies in the knowledge-based economy. This issue can be dealt with from different points of view: the competitive type of functional or nodal regions and
Imre Lengyel
core  

Complex Regulation of RETINOBLASTOMA‐RELATED's Interactions With E2Fs via Phosphorylation

Plant, Cell &Environment, EarlyView.
ABSTRACT Arabidopsis RETINOBLASTOMA‐RELATED (RBR) regulates cell proliferation by interacting with E2F transcription factors and DIMERISATION PARTNER, RB‐LIKE, E2F AND MULTI‐VULVAL CLASS B COMPLEX (DREAM) components. Although CDK‐CYCD phosphorylation is believed to affect RBR's E2F‐binding capacity, the precise phosphorylation events inhibiting RBR's ...
Aladár Pettkó‐Szandtner, Fruzsina Vadai‐Nagy, Magdolna Gombos, Attila Hlacs, Eszter Molnár, Annamária Marton, Csaba Vizler, Rasik Shiekh Bin Hamid, Péter Kaló, Attila Fehér, Zoltán Magyar   +10 more
wiley   +1 more source